Daily Papers

Adapting a pre-trained foundation model on downstream tasks should ensure robustness against distribution shifts without the need to retrain the whole model. Although existing weight interpolation methods are simple yet effective, we argue their static nature limits downstream performance while achieving efficiency. In this work, we propose DaWin, a training-free dynamic weight interpolation method that leverages the entropy of individual models over each unlabeled test sample to assess model expertise, and compute per-sample interpolation coefficients dynamically. Unlike previous works that typically rely on additional training to learn such coefficients, our approach requires no training. Then, we propose a mixture modeling approach that greatly reduces inference overhead raised by dynamic interpolation. We validate DaWin on the large-scale visual recognition benchmarks, spanning 14 tasks across robust fine-tuning -- ImageNet and derived five distribution shift benchmarks -- and multi-task learning with eight classification tasks. Results demonstrate that DaWin achieves significant performance gain in considered settings, with minimal computational overhead. We further discuss DaWin's analytic behavior to explain its empirical success.

As the key component in multimodal large language models (MLLMs), the ability of the visual encoder greatly affects MLLM's understanding on diverse image content. Although some large-scale pretrained vision encoders such as vision encoders in CLIP and DINOv2 have brought promising performance, we found that there is still no single vision encoder that can dominate various image content understanding, e.g., the CLIP vision encoder leads to outstanding results on general image understanding but poor performance on document or chart content. To alleviate the bias of CLIP vision encoder, we first delve into the inherent behavior of different pre-trained vision encoders and then propose the MoVA, a powerful and novel MLLM, adaptively routing and fusing task-specific vision experts with a coarse-to-fine mechanism. In the coarse-grained stage, we design a context-aware expert routing strategy to dynamically select the most suitable vision experts according to the user instruction, input image, and expertise of vision experts. This benefits from the powerful model function understanding ability of the large language model (LLM) equipped with expert-routing low-rank adaptation (LoRA). In the fine-grained stage, we elaborately conduct the mixture-of-vision-expert adapter (MoV-Adapter) to extract and fuse task-specific knowledge from various experts. This coarse-to-fine paradigm effectively leverages representations from experts based on multimodal context and model expertise, further enhancing the generalization ability. We conduct extensive experiments to evaluate the effectiveness of the proposed approach. Without any bells and whistles, MoVA can achieve significant performance gains over current state-of-the-art methods in a wide range of challenging multimodal benchmarks. Codes and models will be available at https://github.com/TempleX98/MoVA.

Model merging, such as model souping, is the practice of combining different models with the same architecture together without further training. In this work, we present a model merging methodology that addresses the difficulty of fine-tuning Large Language Models (LLMs) for target tasks in non-English languages, where task-specific data is often unavailable. We focus on mathematical reasoning and without in-language math data, facilitate cross-lingual transfer by composing language and math capabilities. Starting from the same pretrained model, we fine-tune separate "experts" on math instruction data in English and on generic instruction data in the target language. We then replace the top and bottom transformer layers of the math expert directly with layers from the language expert, which consequently enhances math performance in the target language. The resulting merged models outperform the individual experts and other merging methods on the math benchmark, MGSM, by 10% across four major languages where math instruction data is scarce. In addition, this layer swapping is simple, inexpensive, and intuitive, as it is based on an interpretative analysis of the most important parameter changes during the fine-tuning of each expert. The ability to successfully re-compose LLMs for cross-lingual transfer in this manner opens up future possibilities to combine model expertise, create modular solutions, and transfer reasoning capabilities across languages all post hoc.

Most of the world's languages and dialects are low-resource, and lack support in mainstream machine translation (MT) models. However, many of them have a closely-related high-resource language (HRL) neighbor, and differ in linguistically regular ways from it. This underscores the importance of model robustness to dialectal variation and cross-lingual generalization to the HRL dialect continuum. We present DialUp, consisting of a training-time technique for adapting a pretrained model to dialectal data (M->D), and an inference-time intervention adapting dialectal data to the model expertise (D->M). M->D induces model robustness to potentially unseen and unknown dialects by exposure to synthetic data exemplifying linguistic mechanisms of dialectal variation, whereas D->M treats dialectal divergence for known target dialects. These methods show considerable performance gains for several dialects from four language families, and modest gains for two other language families. We also conduct feature and error analyses, which show that language varieties with low baseline MT performance are more likely to benefit from these approaches.

We study LLM routing, the problem of selecting the best model for each query while balancing user satisfaction, model expertise, and inference cost. We formulate routing as contextual dueling bandits, learning from pairwise preference feedback rather than absolute scores, thereby yielding label-efficient and dynamic adaptation. Building on this formulation, we introduce Category-Calibrated Fine-Tuning (CCFT), a representation-learning method that derives model embeddings from offline data using contrastive fine-tuning with categorical weighting. These embeddings enable the practical instantiation of Feel-Good Thompson Sampling for Contextual Dueling Bandits (FGTS.CDB), a theoretically grounded posterior-sampling algorithm. We propose four variants of the categorical weighting that explicitly integrate model quality and cost, and we empirically evaluate the proposed methods on the RouterBench and MixInstruct datasets. Across both benchmarks, our methods achieve lower cumulative regret and faster convergence, with better robustness and performance-cost balance than strong baselines built with a general-purpose OpenAI embedding model.

Different large language models (LLMs) exhibit diverse strengths and weaknesses, and LLM ensemble serves as a promising approach to integrate their complementary capabilities. Despite substantial progress in improving ensemble quality, limited attention has been paid to the robustness of ensembles against potential erroneous signals, which often arise from heterogeneous tokenization schemes and varying model expertise. Our analysis shows that ensemble failures typically arise from both the token level and the model level: the former reflects severe disagreement in token predictions, while the latter involves low confidence and pronounced disparities among models. In light of this, we propose CoRE, a plug-and-play technique that harnesses model consistency for robust LLM ensemble, which can be seamlessly integrated with diverse ensemble methods. Token-level consistency captures fine-grained disagreements by applying a low-pass filter to downweight uncertain tokens with high inconsistency, often due to token misalignment, thereby improving robustness at a granular level. Model-level consistency models global agreement by promoting model outputs with high self-confidence and minimal divergence from others, enhancing robustness at a coarser level. Extensive experiments across diverse benchmarks, model combinations, and ensemble strategies demonstrate that CoRE consistently improves ensemble performance and robustness.

Several previous studies have considered language- and domain-specific large language models (LLMs) as separate topics. This study explores the combination of a non-English language and a high-demand industry domain, focusing on a Japanese business-specific LLM. This type of a model requires expertise in the business domain, strong language skills, and regular updates of its knowledge. We trained a 13-billion-parameter LLM from scratch using a new dataset of business texts and patents, and continually pretrained it with the latest business documents. Further we propose a new benchmark for Japanese business domain question answering (QA) and evaluate our models on it. The results show that our pretrained model improves QA accuracy without losing general knowledge, and that continual pretraining enhances adaptation to new information. Our pretrained model and business domain benchmark are publicly available.

We propose a method to teach multiple large language models (LLM) to collaborate by interleaving their generations at the token level. We model the decision of which LLM generates the next token as a latent variable. By optimizing the marginal likelihood of a training set under our latent variable model, the base LLM automatically learns when to generate itself and when to call on one of the ``assistant'' language models to generate, all without direct supervision. Token-level collaboration during decoding allows for a fusion of each model's expertise in a manner tailored to the specific task at hand. Our collaborative decoding is especially useful in cross-domain settings where a generalist base LLM learns to invoke domain expert models. On instruction-following, domain-specific QA, and reasoning tasks, we show that the performance of the joint system exceeds that of the individual models. Through qualitative analysis of the learned latent decisions, we show models trained with our method exhibit several interesting collaboration patterns, e.g., template-filling. Our code is available at https://github.com/clinicalml/co-llm.

In the era of large language models, model merging is a promising way to combine multiple task-specific models into a single multitask model without extra training. However, two challenges remain: (a) interference between different models and (b) heterogeneous data during testing. Traditional model merging methods often show significant performance gaps compared to fine-tuned models due to these issues. Additionally, a one-size-fits-all model lacks flexibility for diverse test data, leading to performance degradation. We show that both shared and exclusive task-specific knowledge are crucial for merging performance, but directly merging exclusive knowledge hinders overall performance. In view of this, we propose Twin-Merging, a method that encompasses two principal stages: (1) modularizing knowledge into shared and exclusive components, with compression to reduce redundancy and enhance efficiency; (2) dynamically merging shared and task-specific knowledge based on the input. This approach narrows the performance gap between merged and fine-tuned models and improves adaptability to heterogeneous data. Extensive experiments on 12 datasets for both discriminative and generative tasks demonstrate the effectiveness of our method, showing an average improvement of 28.34% in absolute normalized score for discriminative tasks and even surpassing the fine-tuned upper bound on the generative tasks. (Our implementation is available in https://github.com/LZY-the-boys/Twin-Mergin.)

With the rapid advances of large language models, it becomes increasingly important to systematically evaluate their multilingual and multicultural capabilities. Previous cultural evaluation benchmarks focus mainly on basic cultural knowledge that can be encoded in linguistic form. Here, we propose SommBench, a multilingual benchmark to assess sommelier expertise, a domain deeply grounded in the senses of smell and taste. While language models learn about sensory properties exclusively through textual descriptions, SommBench tests whether this textual grounding is sufficient to emulate expert-level sensory judgment. SommBench comprises three main tasks: Wine Theory Question Answering (WTQA), Wine Feature Completion (WFC), and Food-Wine Pairing (FWP). SommBench is available in multiple languages: English, Slovak, Swedish, Finnish, German, Danish, Italian, and Spanish. This helps separate a language model's wine expertise from its language skills. The benchmark datasets were developed in close collaboration with a professional sommelier and native speakers of the respective languages, resulting in 1,024 wine theory question-answering questions, 1,000 wine feature-completion examples, and 1,000 food-wine pairing examples. We provide results for the most popular language models, including closed-weights models such as Gemini 2.5, and open-weights models, such as GPT-OSS and Qwen 3. Our results show that the most capable models perform well on wine theory question answering (up to 97% correct with a closed-weights model), yet feature completion (peaking at 65%) and food-wine pairing show (MCC ranging between 0 and 0.39) turn out to be more challenging. These results position SommBench as an interesting and challenging benchmark for evaluating the sommelier expertise of language models. The benchmark is publicly available at https://github.com/sommify/sommbench.

In the global drive toward carbon neutrality, deeply coordinated smart energy systems underpin industrial transformation. However, the interdisciplinary, fragmented, and fast-evolving expertise in this domain prevents general-purpose LLMs, which lack domain knowledge and physical-constraint awareness, from delivering precise engineering-aligned inference and generation. To address these challenges, we introduce Helios, a large language model tailored to the smart energy domain, together with a comprehensive suite of resources to advance LLM research in this field. Specifically, we develop Enersys, a multi-agent collaborative framework for end-to-end dataset construction, through which we produce: (1) a smart energy knowledge base, EnerBase, to enrich the model's foundational expertise; (2) an instruction fine-tuning dataset, EnerInstruct, to strengthen performance on domain-specific downstream tasks; and (3) an RLHF dataset, EnerReinforce, to align the model with human preferences and industry standards. Leveraging these resources, Helios undergoes large-scale pretraining, SFT, and RLHF. We also release EnerBench, a benchmark for evaluating LLMs in smart energy scenarios, and demonstrate that our approach significantly enhances domain knowledge mastery, task execution accuracy, and alignment with human preferences.

In the domain of Large Language Model (LLM), LLMs demonstrate significant capabilities in natural language understanding and generation. With the growing needs of applying LLMs on various domains, it is a research question that how to efficiently train and build a model that has expertise in different domains but with a low training cost. We propose CCoE architecture, a framework of easily coupling multiple strong domain experts together to fuse into a big LLM, provides a collective way of utilizing the different domain expert LLMs. Besides, training a large collaborative of multiple expert LLMs requires a high requirements on training sources. CCoE bypasses this problem through isolating other experts and train each expert separately. The design of CCoE assembles multiple expert LLMs through the CoE (Collaboration of Experts) layer. Each CoE layer could have one or more expert LLMs. Expert LLMs have different number of layers and have been well-trained for different domain tasks. Each expert is fine-tuned to be able to achieve the comparable results with SOTA domain LLMs. We start from 5 experts in the domain of Code, Math, Law, text-to-SQL and Medical. The results indicate that our CCoE framework can easily and efficiently boost nearly 10%-20% performance on original base model in different domains but using less resources on training, as well as inference.

This paper investigates the fundamental discontinuity between the latest two Segment Anything Models: SAM2 and SAM3. We explain why the expertise in prompt-based segmentation of SAM2 does not transfer to the multimodal concept-driven paradigm of SAM3. SAM2 operates through spatial prompts points, boxes, and masks yielding purely geometric and temporal segmentation. In contrast, SAM3 introduces a unified vision-language architecture capable of open-vocabulary reasoning, semantic grounding, contrastive alignment, and exemplar-based concept understanding. We structure this analysis through five core components: (1) a Conceptual Break Between Prompt-Based and Concept-Based Segmentation, contrasting spatial prompt semantics of SAM2 with multimodal fusion and text-conditioned mask generation of SAM3; (2) Architectural Divergence, detailing pure vision-temporal design of SAM2 versus integration of vision-language encoders, geometry and exemplar encoders, fusion modules, DETR-style decoders, object queries, and ambiguity-handling via Mixture-of-Experts in SAM3; (3) Dataset and Annotation Differences, contrasting SA-V video masks with multimodal concept-annotated corpora of SAM3; (4) Training and Hyperparameter Distinctions, showing why SAM2 optimization knowledge does not apply to SAM3; and (5) Evaluation, Metrics, and Failure Modes, outlining the transition from geometric IoU metrics to semantic, open-vocabulary evaluation. Together, these analyses establish SAM3 as a new class of segmentation foundation model and chart future directions for the emerging concept-driven segmentation era.

The complexity of legal language and limited accessibility to legal information pose significant challenges to justice delivery in Nepal. Traditional legal services remain inaccessible to many citizens due to language barriers, information fragmentation, and a critical shortage of legal expertise, particularly in rural areas. We present NepLEGiT (Nepali Legal Expertise through Generative and Extractive Pre-trained Transformers), a specialized small language model (SLM) designed to democratize legal knowledge and enhance legal-service delivery in Nepal. We pre-train a decoder-based GPT-2 SLM from scratch on a curated corpus of ~4 million tokens of Nepali legal text, covering constitutional law, civil and criminal codes, and administrative regulations. The model comprises ~30 million parameters in a 6-layer, 6-head, 384-dimensional transformer trained with warmup cosine-decay scheduling, gradient accumulation, and mixed-precision arithmetic. On a held-out validation split, NepLEGiT attains a cross-entropy loss of 0.5684, a perplexity of 1.8, and a next-token prediction accuracy of 82.9%. We further evaluate continual masked-language-model pre-training of mBERT and MuRIL on the same corpus; mBERT achieves a perplexity of 2.35 (eval loss 0.8565), outperforming MuRIL (perplexity 6.07, eval loss 1.8026), providing a strong encoder baseline complementary to NepLEGiT's generative orientation.

Experts advising decision-makers are likely to display expertise which varies as a function of the problem instance. In practice, this may lead to sub-optimal or discriminatory decisions against minority cases. In this work we model such changes in depth and breadth of knowledge as a partitioning of the problem space into regions of differing expertise. We provide here new algorithms that explicitly consider and adapt to the relationship between problem instances and experts' knowledge. We first propose and highlight the drawbacks of a naive approach based on nearest neighbor queries. To address these drawbacks we then introduce a novel algorithm - expertise trees - that constructs decision trees enabling the learner to select appropriate models. We provide theoretical insights and empirically validate the improved performance of our novel approach on a range of problems for which existing methods proved to be inadequate.

Helpful reviews have been essential for the success of e-commerce services, as they help customers make quick purchase decisions and benefit the merchants in their sales. While many reviews are informative, others provide little value and may contain spam, excessive appraisal, or unexpected biases. With the large volume of reviews and their uneven quality, the problem of detecting helpful reviews has drawn much attention lately. Existing methods for identifying helpful reviews primarily focus on review text and ignore the two key factors of (1) who post the reviews and (2) when the reviews are posted. Moreover, the helpfulness votes suffer from scarcity for less popular products and recently submitted (a.k.a., cold-start) reviews. To address these challenges, we introduce a dataset and develop a model that integrates the reviewer's expertise, derived from the past review history of the reviewers, and the temporal dynamics of the reviews to automatically assess review helpfulness. We conduct experiments on our dataset to demonstrate the effectiveness of incorporating these factors and report improved results compared to several well-established baselines.

Large language model (LLM) agents have shown great potential in solving real-world software engineering (SWE) problems. The most advanced open-source SWE agent can resolve over 27% of real GitHub issues in SWE-Bench Lite. However, these sophisticated agent frameworks exhibit varying strengths, excelling in certain tasks while underperforming in others. To fully harness the diversity of these agents, we propose DEI (Diversity Empowered Intelligence), a framework that leverages their unique expertise. DEI functions as a meta-module atop existing SWE agent frameworks, managing agent collectives for enhanced problem-solving. Experimental results show that a DEI-guided committee of agents is able to surpass the best individual agent's performance by a large margin. For instance, a group of open-source SWE agents, with a maximum individual resolve rate of 27.3% on SWE-Bench Lite, can achieve a 34.3% resolve rate with DEI, making a 25% improvement and beating most closed-source solutions. Our best-performing group excels with a 55% resolve rate, securing the highest ranking on SWE-Bench Lite. Our findings contribute to the growing body of research on collaborative AI systems and their potential to solve complex software engineering challenges.

Electrocardiogram (ECG) interpretation requires specialized expertise, often involving synthesizing insights from ECG signals with complex clinical queries posed in natural language. The scarcity of labeled ECG data coupled with the diverse nature of clinical inquiries presents a significant challenge for developing robust and adaptable ECG diagnostic systems. This work introduces a novel multimodal meta-learning method for few-shot ECG question answering, addressing the challenge of limited labeled data while leveraging the rich knowledge encoded within large language models (LLMs). Our LLM-agnostic approach integrates a pre-trained ECG encoder with a frozen LLM (e.g., LLaMA and Gemma) via a trainable fusion module, enabling the language model to reason about ECG data and generate clinically meaningful answers. Extensive experiments demonstrate superior generalization to unseen diagnostic tasks compared to supervised baselines, achieving notable performance even with limited ECG leads. For instance, in a 5-way 5-shot setting, our method using LLaMA-3.1-8B achieves accuracy of 84.6%, 77.3%, and 69.6% on single verify, choose and query question types, respectively. These results highlight the potential of our method to enhance clinical ECG interpretation by combining signal processing with the nuanced language understanding capabilities of LLMs, particularly in data-constrained scenarios.

Vision-Language-Action (VLA) models are experiencing rapid development and demonstrating promising capabilities in robotic manipulation tasks. However, scaling up VLA models presents several critical challenges: (1) Training new VLA models from scratch demands substantial computational resources and extensive datasets. Given the current scarcity of robot data, it becomes particularly valuable to fully leverage well-pretrained VLA model weights during the scaling process. (2) Real-time control requires carefully balancing model capacity with computational efficiency. To address these challenges, We propose AdaMoE, a Mixture-of-Experts (MoE) architecture that inherits pretrained weights from dense VLA models, and scales up the action expert by substituting the feedforward layers into sparsely activated MoE layers. AdaMoE employs a decoupling technique that decouples expert selection from expert weighting through an independent scale adapter working alongside the traditional router. This enables experts to be selected based on task relevance while contributing with independently controlled weights, allowing collaborative expert utilization rather than winner-takes-all dynamics. Our approach demonstrates that expertise need not monopolize. Instead, through collaborative expert utilization, we can achieve superior performance while maintaining computational efficiency. AdaMoE consistently outperforms the baseline model across key benchmarks, delivering performance gains of 1.8% on LIBERO and 9.3% on RoboTwin. Most importantly, a substantial 21.5% improvement in real-world experiments validates its practical effectiveness for robotic manipulation tasks.

Large language model agents often fail to accumulate knowledge from experience, treating each task as an independent challenge. Recent methods extract experience as flattened textual knowledge, which cannot capture procedural logic of complex subtasks. They also lack maintenance mechanisms, causing repository degradation as experience accumulates. We introduce AutoRefine, a framework that extracts and maintains dual-form Experience Patterns from agent execution histories. For procedural subtasks, we extract specialized subagents with independent reasoning and memory. For static knowledge, we extract skill patterns as guidelines or code snippets. A continuous maintenance mechanism scores, prunes, and merges patterns to prevent repository degradation. Evaluated on ALFWorld, ScienceWorld, and TravelPlanner, AutoRefine achieves 98.4%, 70.4%, and 27.1% respectively, with 20-73% step reductions. On TravelPlanner, automatic extraction exceeds manually designed systems (27.1% vs 12.1%), demonstrating its ability to capture procedural coordination.

Model merging provides a compelling paradigm for integrating specialized expertise into a unified multi-task model, a goal that aligns naturally with the sequential knowledge acquisition in continual learning (CL). However, the requirement for preserving diverse forms of previous knowledge conflicts with the storage limitations inherent to CL. In this paper, we systematically analyze existing model merging methods under the constraints of CL. We find that current methods prioritize global alignment, which often leads to the accumulation and amplification of task-specific errors within the continuous data stream; and the vanishing gradients at the onset of subsequent tasks frequently cause optimization to stagnate. These leave the merged model in a suboptimal state at the beginning of the next training phase. To address these challenges, we propose Trajectory Regularized Merging (TRM), a framework that reformulates the merging phase as an optimization process within an augmented trajectory subspace. Our framework integrates three synergistic objectives including task alignment, prediction consistency, and gradient responsiveness to concurrently preserve merged model's historical stability and re-activate optimization dynamics. Extensive experimental results demonstrate that our method achieves state-of-the-art performance across multiple benchmarks.

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical applications remains limited due to the inherent discrepancies between data and tasks in medical scenarios and those in the general domain. Concretely, existing medical MLLMs face the following critical limitations: (1) limited coverage of medical knowledge beyond imaging, (2) heightened susceptibility to hallucinations due to suboptimal data curation processes, (3) lack of reasoning capabilities tailored for complex medical scenarios. To address these challenges, we first propose a comprehensive data curation procedure that (1) efficiently acquires rich medical knowledge data not only from medical imaging but also from extensive medical texts and general-domain data; and (2) synthesizes accurate medical captions, visual question answering (VQA), and reasoning samples. As a result, we build a multimodal dataset enriched with extensive medical knowledge. Building on the curated data, we introduce our medical-specialized MLLM: Lingshu. Lingshu undergoes multi-stage training to embed medical expertise and enhance its task-solving capabilities progressively. Besides, we preliminarily explore the potential of applying reinforcement learning with verifiable rewards paradigm to enhance Lingshu's medical reasoning ability. Additionally, we develop MedEvalKit, a unified evaluation framework that consolidates leading multimodal and textual medical benchmarks for standardized, fair, and efficient model assessment. We evaluate the performance of Lingshu on three fundamental medical tasks, multimodal QA, text-based QA, and medical report generation. The results show that Lingshu consistently outperforms the existing open-source multimodal models on most tasks ...

Generative AI's novel capacities raise questions about the future role of human expertise: does AI level the playing field between professional artists and laypeople, or does expertise enhance AI use? Do the cognitive skills experts make use of in analyzing and drawing visual art also transfer to using these new tools? This pre-registered study conducts experimental comparisons between 50 professional artists and a demographically matched sample of laypeople. Our interdisciplinary team developed two tasks involving image replication and creative image creation, assessing their copying accuracy and divergent thinking. We implemented a bespoke platform for the experiment, powered by a modern text-to-image AI. Results reveal artists produced more accurate copies and more divergent ideas than lay participants, highlighting a skill transfer of professional expertise - even to the confined space of generative AI. We also explored how well an exemplary vision-capable large language model (GPT-4o) would fare: on par in copying and slightly better on average than artists in the creative task, although never above best humans. These findings highlight the importance of integrating artistic skills with AI, suggesting a potential for collaborative synergy that could reshape creative industries and arts education.

Many engineering organizations are reimplementing and extending deep neural networks from the research community. We describe this process as deep learning model reengineering. Deep learning model reengineering - reusing, reproducing, adapting, and enhancing state-of-the-art deep learning approaches - is challenging for reasons including under-documented reference models, changing requirements, and the cost of implementation and testing. In addition, individual engineers may lack expertise in software engineering, yet teams must apply knowledge of software engineering and deep learning to succeed. Prior work has examined on DL systems from a "product" view, examining defects from projects regardless of the engineers' purpose. Our study is focused on reengineering activities from a "process" view, and focuses on engineers specifically engaged in the reengineering process. Our goal is to understand the characteristics and challenges of deep learning model reengineering. We conducted a case study of this phenomenon, focusing on the context of computer vision. Our results draw from two data sources: defects reported in open-source reeengineering projects, and interviews conducted with open-source project contributors and the leaders of a reengineering team. Our results describe how deep learning-based computer vision techniques are reengineered, analyze the distribution of defects in this process, and discuss challenges and practices. Integrating our quantitative and qualitative data, we proposed a novel reengineering workflow. Our findings inform several future directions, including: measuring additional unknown aspects of model reengineering; standardizing engineering practices to facilitate reengineering; and developing tools to support model reengineering and model reuse.

Designing de novo proteins beyond those found in nature holds significant promise for advancements in both scientific and engineering applications. Current methodologies for protein design often rely on AI-based models, such as surrogate models that address end-to-end problems by linking protein structure to material properties or vice versa. However, these models frequently focus on specific material objectives or structural properties, limiting their flexibility when incorporating out-of-domain knowledge into the design process or comprehensive data analysis is required. In this study, we introduce ProtAgents, a platform for de novo protein design based on Large Language Models (LLMs), where multiple AI agents with distinct capabilities collaboratively address complex tasks within a dynamic environment. The versatility in agent development allows for expertise in diverse domains, including knowledge retrieval, protein structure analysis, physics-based simulations, and results analysis. The dynamic collaboration between agents, empowered by LLMs, provides a versatile approach to tackling protein design and analysis problems, as demonstrated through diverse examples in this study. The problems of interest encompass designing new proteins, analyzing protein structures and obtaining new first-principles data -- natural vibrational frequencies -- via physics simulations. The concerted effort of the system allows for powerful automated and synergistic design of de novo proteins with targeted mechanical properties. The flexibility in designing the agents, on one hand, and their capacity in autonomous collaboration through the dynamic LLM-based multi-agent environment on the other hand, unleashes great potentials of LLMs in addressing multi-objective materials problems and opens up new avenues for autonomous materials discovery and design.

Decision-makers are often experts of their domain and take actions based on their domain knowledge. Doctors, for instance, may prescribe treatments by predicting the likely outcome of each available treatment. Actions of an expert thus naturally encode part of their domain knowledge, and can help make inferences within the same domain: Knowing doctors try to prescribe the best treatment for their patients, we can tell treatments prescribed more frequently are likely to be more effective. Yet in machine learning, the fact that most decision-makers are experts is often overlooked, and "expertise" is seldom leveraged as an inductive bias. This is especially true for the literature on treatment effect estimation, where often the only assumption made about actions is that of overlap. In this paper, we argue that expertise - particularly the type of expertise the decision-makers of a domain are likely to have - can be informative in designing and selecting methods for treatment effect estimation. We formally define two types of expertise, predictive and prognostic, and demonstrate empirically that: (i) the prominent type of expertise in a domain significantly influences the performance of different methods in treatment effect estimation, and (ii) it is possible to predict the type of expertise present in a dataset, which can provide a quantitative basis for model selection.

Merging Large Language Models (LLMs) is a cost-effective technique for combining multiple expert LLMs into a single versatile model, retaining the expertise of the original ones. However, current approaches often overlook the importance of safety alignment during merging, leading to highly misaligned models. This work investigates the effects of model merging on alignment. We evaluate several popular model merging techniques, demonstrating that existing methods do not only transfer domain expertise but also propagate misalignment. We propose a simple two-step approach to address this problem: (i) generating synthetic safety and domain-specific data, and (ii) incorporating these generated data into the optimization process of existing data-aware model merging techniques. This allows us to treat alignment as a skill that can be maximized in the resulting merged LLM. Our experiments illustrate the effectiveness of integrating alignment-related data during merging, resulting in models that excel in both domain expertise and alignment.

Large language models (LLMs) increasingly demonstrate signs of conceptual understanding, yet much of their internal knowledge remains latent, loosely structured, and difficult to access or evaluate. We propose self-questioning as a lightweight and scalable strategy to improve LLMs' understanding, particularly in domains where success depends on fine-grained semantic distinctions. To evaluate this approach, we introduce a challenging new benchmark of 1.3 million post-2015 computer science patent pairs, characterized by dense technical jargon and strategically complex writing. The benchmark centers on a pairwise differentiation task: can a model distinguish between closely related but substantively different inventions? We show that prompting LLMs to generate and answer their own questions - targeting the background knowledge required for the task - significantly improves performance. These self-generated questions and answers activate otherwise underutilized internal knowledge. Allowing LLMs to retrieve answers from external scientific texts further enhances performance, suggesting that model knowledge is compressed and lacks the full richness of the training data. We also find that chain-of-thought prompting and self-questioning converge, though self-questioning remains more effective for improving understanding of technical concepts. Notably, we uncover an asymmetry in prompting: smaller models often generate more fundamental, more open-ended, better-aligned questions for mid-sized models than large models with better understanding do, revealing a new strategy for cross-model collaboration. Altogether, our findings establish self-questioning as both a practical mechanism for automatically improving LLM comprehension, especially in domains with sparse and underrepresented knowledge, and a diagnostic probe of how internal and external knowledge are organized.

Current fundus image analysis models are predominantly built for specific tasks relying on individual datasets. The learning process is usually based on data-driven paradigm without prior knowledge, resulting in poor transferability and generalizability. To address this issue, we propose MM-Retinal, a multi-modal dataset that encompasses high-quality image-text pairs collected from professional fundus diagram books. Moreover, enabled by MM-Retinal, we present a novel Knowledge-enhanced foundational pretraining model which incorporates Fundus Image-Text expertise, called KeepFIT. It is designed with image similarity-guided text revision and mixed training strategy to infuse expert knowledge. Our proposed fundus foundation model achieves state-of-the-art performance across six unseen downstream tasks and holds excellent generalization ability in zero-shot and few-shot scenarios. MM-Retinal and KeepFIT are available at https://github.com/lxirich/MM-Retinal.

Matching submissions with suitable reviewers at scale is a growing challenge for major venues, yet existing approaches either rely on coarse proxy signals that conflate general relatedness with true suitability, or require expensive human annotations that are difficult to scale for training. We propose MERIT, a two-stage framework that bridges this gap by converting criterion-level expertise matching into scalable suitability supervision. In the first stage, we train a reviewer assessor via reinforcement learning to identify the expertise dimensions a paper requires, match them against the reviewer's prior work, and produce a suitability decision, with rewards provided by an LLM judge guided by paper-specific expertise rubrics. In the second stage, we distill the assessor's predictions into an embedding-based retriever for efficient large-scale assignment. Experiments show that our 4B reviewer assessor outperforms larger general-purpose LLMs on suitability classification, and the resulting retriever achieves state-of-the-art performance across LR-Bench and the CMU Gold dataset. Our code is available at https://github.com/Luli3220/MERIT.

BalancedBio is a theoretically grounded framework for parameter-efficient biomedical reasoning, addressing multi-capability integration in domain-specific AI alignment. It establishes the Biomedical Multi-Capability Convergence Theorem, proving orthogonal gradient spaces are essential to prevent capability interference for safe deployment. Key innovations include: (1) Medical Knowledge Grounded Synthetic Generation (MKGSG), extending Source2Synth with clinical workflow constraints and medical ontology validation for factual accuracy and safety; and (2) Capability Aware Group Relative Policy Optimization, deriving optimal hybrid reward weighting to maintain orthogonality in RL, using a reward model with rule-based and model-based scores adapted to biomedical tasks. Mathematical analysis proves Pareto-optimal convergence, preserving performance across capabilities. It achieves state-of-the-art results in its parameter class: domain expertise (80.95% BIOMED-MMLU, +15.32% over baseline), reasoning (61.94%, +7.75%), instruction following (67.95%, +6.44%), and integration (86.7%, +18.5%). Theoretical safety guarantees include bounds on capability preservation and clinical accuracy. Real-world deployment yields 78% cost reduction, 23% improved diagnostic accuracy, and 89% clinician acceptance. This work provides a principled methodology for biomedical AI alignment, enabling efficient reasoning with essential safety and reliability, with the 0.5B model version to be released.

Operational flood forecasting depends on tacit forecaster expertise that is difficult to formalize, audit, and transfer. Although artificial intelligence methods have advanced flood prediction and model-error correction, most existing studies have not explicitly represented the tacit expert rules, review checkpoints, and workflow constraints that connect model outputs to operational warning decisions. To address this issue, we propose HydroAgent, a skill-orchestrated agent framework that embeds Large Language Models (LLMs) into a model-driven flood forecasting workflow, where each skill encodes explicit rules to bound LLM reasoning. We validated its effectiveness using five state-of-the-art LLMs in the South Yamhill River basin. Our results demonstrate that prior judgment captures observed peak flow and flood volume within 5% tolerance in 10 and 11 out of 14 events, with 5-fold cross-validation over 129 events yielding Pearson correlations of 0.62 and 0.84. Building on a high-baseline scheme library (average KGE 0.890), the guided scheme selection further improves KGE by 0.023-0.154, with simulated peak flow and flood volume falling within the prior judgment ranges for 14 and 13 out of 14 events. All five tested LLMs successfully execute the HydroAgent workflow with comparable judgment accuracy (40%-80%), while showing moderate performance variation and substantial cost differences. HydroAgent does not aim to replace human forecasters; instead, it translates their tacit expertise into an auditable and reproducible workflow, streamlining analytical steps and supporting more informed decision-making. This skill-orchestrated paradigm demonstrates how explicit rule boundaries can guide language model reasoning to complement physically based simulation in next-generation flood forecasting.

Graphic layout generation, a growing research field, plays a significant role in user engagement and information perception. Existing methods primarily treat layout generation as a numerical optimization task, focusing on quantitative aspects while overlooking the semantic information of layout, such as the relationship between each layout element. In this paper, we propose LayoutNUWA, the first model that treats layout generation as a code generation task to enhance semantic information and harness the hidden layout expertise of large language models~(LLMs). More concretely, we develop a Code Instruct Tuning (CIT) approach comprising three interconnected modules: 1) the Code Initialization (CI) module quantifies the numerical conditions and initializes them as HTML code with strategically placed masks; 2) the Code Completion (CC) module employs the formatting knowledge of LLMs to fill in the masked portions within the HTML code; 3) the Code Rendering (CR) module transforms the completed code into the final layout output, ensuring a highly interpretable and transparent layout generation procedure that directly maps code to a visualized layout. We attain significant state-of-the-art performance (even over 50\% improvements) on multiple datasets, showcasing the strong capabilities of LayoutNUWA. Our code is available at https://github.com/ProjectNUWA/LayoutNUWA.

Recent works have demonstrated the effectiveness of self-alignment in which a large language model is, by itself, aligned to follow general instructions through the automatic generation of instructional data using a handful of human-written seeds. Instead of general alignment, in this work, we focus on self-alignment for expert domain specialization (e.g., biomedicine), discovering it to be very effective for improving zero-shot and few-shot performance in target domains of interest. As a preliminary, we first present the benchmark results of existing aligned models within a specialized domain, which reveals the marginal effect that "generic" instruction-following training has on downstream expert domains' performance. To remedy this, we explore self-specialization that leverages domain-specific unlabelled data and a few labeled seeds for the self-alignment process. When augmented with retrieval to reduce hallucination and enhance concurrency of the alignment, self-specialization offers an effective (and efficient) way of "carving out" an expert model out of a "generalist", pre-trained LLM where different domains of expertise are originally combined in a form of "superposition". Our experimental results on a biomedical domain show that our self-specialized model (30B) outperforms its base model, MPT-30B by a large margin and even surpasses larger popular models based on LLaMA-65B, highlighting its potential and practicality for specialization, especially considering its efficiency in terms of data and parameters.

Large Language Models (LLMs) have exhibited impressive capabilities in various tasks, yet their vast parameter sizes restrict their applicability in resource-constrained settings. Knowledge distillation (KD) offers a viable solution by transferring expertise from large teacher models to compact student models. However, traditional KD techniques face specific challenges when applied to LLMs, including restricted access to LLM outputs, significant teacher-student capacity gaps, and the inherited mis-calibration issue. In this work, we present PLaD, a novel preference-based LLM distillation framework. PLaD exploits the teacher-student capacity discrepancy to generate pseudo-preference pairs where teacher outputs are preferred over student outputs. Then, PLaD leverages a ranking loss to re-calibrate student's estimation of sequence likelihood, which steers the student's focus towards understanding the relative quality of outputs instead of simply imitating the teacher. PLaD bypasses the need for access to teacher LLM's internal states, tackles the student's expressivity limitations, and mitigates the student mis-calibration issue. Through extensive experiments on two sequence generation tasks and with various LLMs, we demonstrate the effectiveness of our proposed PLaD framework.

The cultivation of expertise for large language models (LLMs) to solve tasks of specific areas often requires special-purpose tuning with calibrated behaviors on the expected stable outputs. To avoid huge cost brought by manual preparation of instruction datasets and training resources up to hundreds of hours, the exploitation of open knowledge including a wealth of low rank adaptation (LoRA) models and instruction datasets serves as a good starting point. However, existing methods on model and data selection focus on the performance of general-purpose capabilities while neglecting the knowledge gap exposed in domain-specific deployment. In the present study, we propose to bridge such gap by introducing few human-annotated samples (i.e., K-shot) for advancing task expertise of LLMs with open knowledge. Specifically, we develop an efficient and scalable pipeline to cost-efficiently produce task experts where K-shot data intervene in selecting the most promising expert candidates and the task-relevant instructions. A mixture-of-expert (MoE) system is built to make the best use of individual-yet-complementary knowledge between multiple experts. We unveil the two keys to the success of a MoE system, 1) the abidance by K-shot, and 2) the insistence on diversity. For the former, we ensure that models that truly possess problem-solving abilities on K-shot are selected rather than those blind guessers. Besides, during data selection, instructions that share task-relevant contexts with K-shot are prioritized. For the latter, we highlight the diversity of constituting experts and that of the fine-tuning instructions throughout the model and data selection process. Extensive experimental results confirm the superiority of our approach over existing methods on utilization of open knowledge across various tasks. Codes and models will be released later.

Large language models (LLMs) have achieved remarkable progress in code generation, yet their true programming competence remains underexplored. We introduce the Code Triangle framework, which systematically evaluates LLMs across three fundamental dimensions: editorial analysis, code implementation, and test case generation. Through extensive experiments on competitive programming benchmarks, we reveal that while LLMs can form a self-consistent system across these dimensions, their solutions often lack the diversity and robustness of human programmers. We identify a significant distribution shift between model cognition and human expertise, with model errors tending to cluster due to training data biases and limited reasoning transfer. Our study demonstrates that incorporating human-generated editorials, solutions, and diverse test cases, as well as leveraging model mixtures, can substantially enhance both the performance and robustness of LLMs. Furthermore, we reveal both the consistency and inconsistency in the cognition of LLMs that may facilitate self-reflection and self-improvement, providing a potential direction for developing more powerful coding models.

Configuring computational fluid dynamics (CFD) simulations typically demands extensive domain expertise, limiting broader access. Although large language models (LLMs) have advanced scientific computing, their use in automating CFD workflows is underdeveloped. We introduce a novel approach centered on domain-specific LLM adaptation. By fine-tuning Qwen2.5-7B-Instruct on NL2FOAM, our custom dataset of 28716 natural language-to-OpenFOAM configuration pairs with chain-of-thought (CoT) annotations, we enable direct translation from natural language descriptions to executable CFD setups. A multi-agent framework orchestrates the process, autonomously verifying inputs, generating configurations, running simulations, and correcting errors. Evaluation on a benchmark of 21 diverse flow cases demonstrates state-of-the-art performance, achieving 88.7% solution accuracy and 82.6% first-attempt success rate. This significantly outperforms larger general-purpose models like Qwen2.5-72B-Instruct, DeepSeek-R1, and Llama3.3-70B-Instruct, while also requiring fewer correction iterations and maintaining high computational efficiency. The results highlight the critical role of domain-specific adaptation in deploying LLM assistants for complex engineering workflows. Our code and fine-tuned model have been deposited at https://github.com/YYgroup/AutoCFD.

We introduce Intern-S1-Pro, the first one-trillion-parameter scientific multimodal foundation model. Scaling to this unprecedented size, the model delivers a comprehensive enhancement across both general and scientific domains. Beyond stronger reasoning and image-text understanding capabilities, its intelligence is augmented with advanced agent capabilities. Simultaneously, its scientific expertise has been vastly expanded to master over 100 specialized tasks across critical science fields, including chemistry, materials, life sciences, and earth sciences. Achieving this massive scale is made possible by the robust infrastructure support of XTuner and LMDeploy, which facilitates highly efficient Reinforcement Learning (RL) training at the 1-trillion parameter level while ensuring strict precision consistency between training and inference. By seamlessly integrating these advancements, Intern-S1-Pro further fortifies the fusion of general and specialized intelligence, working as a Specializable Generalist, demonstrating its position in the top tier of open-source models for general capabilities, while outperforming proprietary models in the depth of specialized scientific tasks.

Data augmentation is a widely used strategy to improve model robustness and generalization by enriching training datasets with synthetic examples. While large language models (LLMs) have demonstrated strong generative capabilities for this purpose, their applications in high-stakes domains like healthcare present unique challenges due to the risk of generating clinically incorrect or misleading information. In this work, we propose a novel query-based model collaboration framework that integrates expert-level domain knowledge to guide the augmentation process to preserve critical medical information. Experiments on clinical prediction tasks demonstrate that our lightweight collaboration-based approach consistently outperforms existing LLM augmentation methods while improving safety through reduced factual errors. This framework addresses the gap between LLM augmentation potential and the safety requirements of specialized domains.

Time series reasoning is essential for real-world problem-solving. While both Large Language Models (LLMs) and Vision-Language Models (VLMs) can reason about time-series data, their capabilities are complementary: LLMs process time series as text sequences and thus preserve exact numerical understanding, but struggle with global patterns, whereas VLMs efficiently capture these patterns by visualizing time series but may lose fine-grained details. Moreover, models vary significantly in task-specific expertise and inference costs. Dynamically selecting the most suitable modality and model for each query is therefore crucial, yet challenging because it requires modeling the complex interactions among tasks, queries, modalities, and models, which carry rich contextual signals. To this end, we introduce TSRouter, a graph-based dynamic routing framework. TSRouter constructs a heterogeneous graph of task, query, modality, and model nodes to contextualize the interactions among query characteristics, modality attributes, and model capabilities. TSRouter formulates routing as a candidate scoring problem, where each modality-model pair is evaluated based on user-defined performance-cost preferences to select the optimal candidate. Comprehensive evaluations on 4 distinct time series reasoning tasks reveal that TSRouter substantially outperforms diverse baselines with 16\% to 46\% relative improvements. Furthermore, TSRouter demonstrates robust zero-shot plug-and-play generalization to unseen models and novel tasks and preserves high performance while reducing computational overhead through cost-aware optimization. Our code is available at https://github.com/tianyi-lab/TSRouter.

Machine learning (ML) models have significantly grown in complexity and utility, driving advances across multiple domains. However, substantial computational resources and specialized expertise have historically restricted their wide adoption. Machine-Learning-as-a-Service (MLaaS) platforms have addressed these barriers by providing scalable, convenient, and affordable access to sophisticated ML models through user-friendly APIs. While this accessibility promotes widespread use of advanced ML capabilities, it also introduces vulnerabilities exploited through Model Extraction Attacks (MEAs). Recent studies have demonstrated that adversaries can systematically replicate a target model's functionality by interacting with publicly exposed interfaces, posing threats to intellectual property, privacy, and system security. In this paper, we offer a comprehensive survey of MEAs and corresponding defense strategies. We propose a novel taxonomy that classifies MEAs according to attack mechanisms, defense approaches, and computing environments. Our analysis covers various attack techniques, evaluates their effectiveness, and highlights challenges faced by existing defenses, particularly the critical trade-off between preserving model utility and ensuring security. We further assess MEAs within different computing paradigms and discuss their technical, ethical, legal, and societal implications, along with promising directions for future research. This systematic survey aims to serve as a valuable reference for researchers, practitioners, and policymakers engaged in AI security and privacy. Additionally, we maintain an online repository continuously updated with related literature at https://github.com/kzhao5/ModelExtractionPapers.

Efficient creation of accurate and editable 3D CAD models is critical in engineering design, significantly impacting cost and time-to-market in product innovation. Current manual workflows remain highly time-consuming and demand extensive user expertise. While recent developments in AI-driven CAD generation show promise, existing models are limited by incomplete representations of CAD operations, inability to generalize to real-world images, and low output accuracy. This paper introduces CAD-Coder, an open-source Vision-Language Model (VLM) explicitly fine-tuned to generate editable CAD code (CadQuery Python) directly from visual input. Leveraging a novel dataset that we created--GenCAD-Code, consisting of over 163k CAD-model image and code pairs--CAD-Coder outperforms state-of-the-art VLM baselines such as GPT-4.5 and Qwen2.5-VL-72B, achieving a 100% valid syntax rate and the highest accuracy in 3D solid similarity. Notably, our VLM demonstrates some signs of generalizability, successfully generating CAD code from real-world images and executing CAD operations unseen during fine-tuning. The performance and adaptability of CAD-Coder highlights the potential of VLMs fine-tuned on code to streamline CAD workflows for engineers and designers. CAD-Coder is publicly available at: https://github.com/anniedoris/CAD-Coder.

Training AI models that generalize across tasks and domains has long been among the open problems driving AI research. The emergence of Foundation Models made it easier to obtain expert models for a given task, but the heterogeneity of data that may be encountered at test time often means that any single expert is insufficient. We consider the Fusion of Experts (FoE) problem of fusing outputs of expert models with complementary knowledge of the data distribution and formulate it as an instance of supervised learning. Our method is applicable to both discriminative and generative tasks and leads to significant performance improvements in image and text classification, text summarization, multiple-choice QA, and automatic evaluation of generated text. We also extend our method to the "frugal" setting where it is desired to reduce the number of expert model evaluations at test time.

We present Diffusion Model Patching (DMP), a simple method to boost the performance of pre-trained diffusion models that have already reached convergence, with a negligible increase in parameters. DMP inserts a small, learnable set of prompts into the model's input space while keeping the original model frozen. The effectiveness of DMP is not merely due to the addition of parameters but stems from its dynamic gating mechanism, which selects and combines a subset of learnable prompts at every step of the generative process (e.g., reverse denoising steps). This strategy, which we term "mixture-of-prompts", enables the model to draw on the distinct expertise of each prompt, essentially "patching" the model's functionality at every step with minimal yet specialized parameters. Uniquely, DMP enhances the model by further training on the same dataset on which it was originally trained, even in a scenario where significant improvements are typically not expected due to model convergence. Experiments show that DMP significantly enhances the converged FID of DiT-L/2 on FFHQ 256x256 by 10.38%, achieved with only a 1.43% parameter increase and 50K additional training iterations.

Ocean science, which delves into the oceans that are reservoirs of life and biodiversity, is of great significance given that oceans cover over 70% of our planet's surface. Recently, advances in Large Language Models (LLMs) have transformed the paradigm in science. Despite the success in other domains, current LLMs often fall short in catering to the needs of domain experts like oceanographers, and the potential of LLMs for ocean science is under-explored. The intrinsic reasons are the immense and intricate nature of ocean data as well as the necessity for higher granularity and richness in knowledge. To alleviate these issues, we introduce OceanGPT, the first-ever large language model in the ocean domain, which is expert in various ocean science tasks. We also propose OceanGPT, a novel framework to automatically obtain a large volume of ocean domain instruction data, which generates instructions based on multi-agent collaboration. Additionally, we construct the first oceanography benchmark, OceanBench, to evaluate the capabilities of LLMs in the ocean domain. Though comprehensive experiments, OceanGPT not only shows a higher level of knowledge expertise for oceans science tasks but also gains preliminary embodied intelligence capabilities in ocean technology.

The recent advance in Large Language Models (LLMs) has shaped a new paradigm of AI agents, i.e., LLM-based agents. Compared to standalone LLMs, LLM-based agents substantially extend the versatility and expertise of LLMs by enhancing LLMs with the capabilities of perceiving and utilizing external resources and tools. To date, LLM-based agents have been applied and shown remarkable effectiveness in Software Engineering (SE). The synergy between multiple agents and human interaction brings further promise in tackling complex real-world SE problems. In this work, we present a comprehensive and systematic survey on LLM-based agents for SE. We collect 106 papers and categorize them from two perspectives, i.e., the SE and agent perspectives. In addition, we discuss open challenges and future directions in this critical domain. The repository of this survey is at https://github.com/FudanSELab/Agent4SE-Paper-List.

Medical image segmentation has immense clinical applicability but remains a challenge despite advancements in deep learning. The Segment Anything Model (SAM) exhibits potential in this field, yet the requirement for expertise intervention and the domain gap between natural and medical images poses significant obstacles. This paper introduces a novel training-free evidential prompt generation method named EviPrompt to overcome these issues. The proposed method, built on the inherent similarities within medical images, requires only a single reference image-annotation pair, making it a training-free solution that significantly reduces the need for extensive labeling and computational resources. First, to automatically generate prompts for SAM in medical images, we introduce an evidential method based on uncertainty estimation without the interaction of clinical experts. Then, we incorporate the human prior into the prompts, which is vital for alleviating the domain gap between natural and medical images and enhancing the applicability and usefulness of SAM in medical scenarios. EviPrompt represents an efficient and robust approach to medical image segmentation, with evaluations across a broad range of tasks and modalities confirming its efficacy.

Frontier AI safety policies highlight automation of AI research and development (R&D) by AI agents as an important capability to anticipate. However, there exist few evaluations for AI R&D capabilities, and none that are highly realistic and have a direct comparison to human performance. We introduce RE-Bench (Research Engineering Benchmark, v1), which consists of 7 challenging, open-ended ML research engineering environments and data from 71 8-hour attempts by 61 distinct human experts. We confirm that our experts make progress in the environments given 8 hours, with 82% of expert attempts achieving a non-zero score and 24% matching or exceeding our strong reference solutions. We compare humans to several public frontier models through best-of-k with varying time budgets and agent designs, and find that the best AI agents achieve a score 4x higher than human experts when both are given a total time budget of 2 hours per environment. However, humans currently display better returns to increasing time budgets, narrowly exceeding the top AI agent scores given an 8-hour budget, and achieving 2x the score of the top AI agent when both are given 32 total hours (across different attempts). Qualitatively, we find that modern AI agents possess significant expertise in many ML topics -- e.g. an agent wrote a faster custom Triton kernel than any of our human experts' -- and can generate and test solutions over ten times faster than humans, at much lower cost. We open-source the evaluation environments, human expert data, analysis code and agent trajectories to facilitate future research.

Data-driven scientific discovery requires the iterative integration of scientific domain knowledge, statistical expertise, and an understanding of data semantics to make nuanced analytical decisions, e.g., about which variables, transformations, and statistical models to consider. LM-based agents equipped with planning, memory, and code execution capabilities have the potential to support data-driven science. However, evaluating agents on such open-ended tasks is challenging due to multiple valid approaches, partially correct steps, and different ways to express the same decisions. To address these challenges, we present BLADE, a benchmark to automatically evaluate agents' multifaceted approaches to open-ended research questions. BLADE consists of 12 datasets and research questions drawn from existing scientific literature, with ground truth collected from independent analyses by expert data scientists and researchers. To automatically evaluate agent responses, we developed corresponding computational methods to match different representations of analyses to this ground truth. Though language models possess considerable world knowledge, our evaluation shows that they are often limited to basic analyses. However, agents capable of interacting with the underlying data demonstrate improved, but still non-optimal, diversity in their analytical decision making. Our work enables the evaluation of agents for data-driven science and provides researchers deeper insights into agents' analysis approaches.

Current research is primarily dedicated to advancing the accuracy of camera-only 3D object detectors (apprentice) through the knowledge transferred from LiDAR- or multi-modal-based counterparts (expert). However, the presence of the domain gap between LiDAR and camera features, coupled with the inherent incompatibility in temporal fusion, significantly hinders the effectiveness of distillation-based enhancements for apprentices. Motivated by the success of uni-modal distillation, an apprentice-friendly expert model would predominantly rely on camera features, while still achieving comparable performance to multi-modal models. To this end, we introduce VCD, a framework to improve the camera-only apprentice model, including an apprentice-friendly multi-modal expert and temporal-fusion-friendly distillation supervision. The multi-modal expert VCD-E adopts an identical structure as that of the camera-only apprentice in order to alleviate the feature disparity, and leverages LiDAR input as a depth prior to reconstruct the 3D scene, achieving the performance on par with other heterogeneous multi-modal experts. Additionally, a fine-grained trajectory-based distillation module is introduced with the purpose of individually rectifying the motion misalignment for each object in the scene. With those improvements, our camera-only apprentice VCD-A sets new state-of-the-art on nuScenes with a score of 63.1% NDS.

Ultrasound imaging has become the preferred imaging modality for early cancer screening due to its advantages of non-ionizing radiation, low cost, and real-time imaging capabilities. However, conventional ultrasound diagnosis heavily relies on physician expertise, presenting challenges of high subjectivity and low diagnostic efficiency. Vision-language models (VLMs) offer promising solutions for this issue, but existing general-purpose models demonstrate limited knowledge in ultrasound medical tasks, with poor generalization in multi-organ lesion recognition and low efficiency across multi-task diagnostics. To address these limitations, we propose EchoVLM, a vision-language model specifically designed for ultrasound medical imaging. The model employs a Mixture of Experts (MoE) architecture trained on data spanning seven anatomical regions. This design enables the model to perform multiple tasks, including ultrasound report generation, diagnosis and visual question-answering (VQA). The experimental results demonstrated that EchoVLM achieved significant improvements of 10.15 and 4.77 points in BLEU-1 scores and ROUGE-1 scores respectively compared to Qwen2-VL on the ultrasound report generation task. These findings suggest that EchoVLM has substantial potential to enhance diagnostic accuracy in ultrasound imaging, thereby providing a viable technical solution for future clinical applications. Source code and model weights are available at https://github.com/Asunatan/EchoVLM.

In the domain of model-based engineering, models are essential components that enable system design and analysis. Traditionally, the creation of these models has been a manual process requiring not only deep modeling expertise but also substantial domain knowledge of target systems. With the rapid advancement of generative artificial intelligence, large language models (LLMs) show potential for automating model generation. This work explores the generation of instance models using LLMs, focusing specifically on producing XMI-based instance models from Ecore metamodels and natural language specifications. We observe that current LLMs struggle to directly generate valid XMI models. To address this, we propose a two-step approach: first, using LLMs to produce a simplified structured output containing all necessary instance model information, namely a conceptual instance model, and then compiling this intermediate representation into a valid XMI file. The conceptual instance model is format-independent, allowing it to be transformed into various modeling formats via different compilers. The feasibility of the proposed method has been demonstrated using several LLMs, including GPT-4o, o1-preview, Llama 3.1 (8B and 70B). Results show that the proposed method significantly improves the usability of LLMs for instance model generation tasks. Notably, the smaller open-source model, Llama 3.1 70B, demonstrated performance comparable to proprietary GPT models within the proposed framework.

Formal theorem proving with TLA+ provides rigorous guarantees for system specifications, but constructing proofs requires substantial expertise and effort. While large language models have shown promise in automating proofs for tactic-based theorem provers like Lean, applying these approaches directly to TLA+ faces significant challenges due to the hierarchical proof structure of the TLA+ proof system. We present a prompt-based approach that leverages LLMs to guide hierarchical decomposition of complex proof obligations into simpler sub-claims, while relying on symbolic provers for verification. Our key insight is to constrain LLMs to generate normalized claim decompositions rather than complete proofs, significantly reducing syntax errors. We also introduce a benchmark suite of 119 theorems adapted from (1) established mathematical collections and (2) inductive proofs of distributed protocols. Our approach consistently outperforms baseline methods across the benchmark suite.

There are an increasing number of domains in which artificial intelligence (AI) systems both surpass human ability and accurately model human behavior. This introduces the possibility of algorithmically-informed teaching in these domains through more relatable AI partners and deeper insights into human decision-making. Critical to achieving this goal, however, is coherently modeling human behavior at various skill levels. Chess is an ideal model system for conducting research into this kind of human-AI alignment, with its rich history as a pivotal testbed for AI research, mature superhuman AI systems like AlphaZero, and precise measurements of skill via chess rating systems. Previous work in modeling human decision-making in chess uses completely independent models to capture human style at different skill levels, meaning they lack coherence in their ability to adapt to the full spectrum of human improvement and are ultimately limited in their effectiveness as AI partners and teaching tools. In this work, we propose a unified modeling approach for human-AI alignment in chess that coherently captures human style across different skill levels and directly captures how people improve. Recognizing the complex, non-linear nature of human learning, we introduce a skill-aware attention mechanism to dynamically integrate players' strengths with encoded chess positions, enabling our model to be sensitive to evolving player skill. Our experimental results demonstrate that this unified framework significantly enhances the alignment between AI and human players across a diverse range of expertise levels, paving the way for deeper insights into human decision-making and AI-guided teaching tools.

Ultrasound imaging is widely used in clinical diagnosis due to its non-invasive nature and real-time capabilities. However, traditional ultrasound diagnostics relies heavily on physician expertise and is often hampered by suboptimal image quality, leading to potential diagnostic errors. While artificial intelligence (AI) offers a promising solution to enhance clinical diagnosis by detecting abnormalities across various imaging modalities, existing AI methods for ultrasound face two major challenges. First, they typically require vast amounts of labeled medical data, raising serious concerns regarding patient privacy. Second, most models are designed for specific tasks, which restricts their broader clinical utility. To overcome these challenges, we present UltraFedFM, an innovative privacy-preserving ultrasound foundation model. UltraFedFM is collaboratively pre-trained using federated learning across 16 distributed medical institutions in 9 countries, leveraging a dataset of over 1 million ultrasound images covering 19 organs and 10 ultrasound modalities. This extensive and diverse data, combined with a secure training framework, enables UltraFedFM to exhibit strong generalization and diagnostic capabilities. It achieves an average area under the receiver operating characteristic curve (AUROC) of 0.927 for disease diagnosis and a dice similarity coefficient (DSC) of 0.878 for lesion segmentation. Notably, UltraFedFM surpasses the diagnostic accuracy of mid-level ultrasonographers (4-8 years of experience) and matches the performance of expert-level sonographers (10+ years of experience) in the joint diagnosis of 8 common systemic diseases.c These findings indicate that UltraFedFM can significantly enhance clinical diagnostics while safeguarding patient privacy, marking a significant advancement in AI-driven ultrasound imaging for future clinical applications.

Deep learning models for natural language processing (NLP) are increasingly adopted and deployed by analysts without formal training in NLP or machine learning (ML). However, the documentation intended to convey the model's details and appropriate use is tailored primarily to individuals with ML or NLP expertise. To address this gap, we conduct a design inquiry into interactive model cards, which augment traditionally static model cards with affordances for exploring model documentation and interacting with the models themselves. Our investigation consists of an initial conceptual study with experts in ML, NLP, and AI Ethics, followed by a separate evaluative study with non-expert analysts who use ML models in their work. Using a semi-structured interview format coupled with a think-aloud protocol, we collected feedback from a total of 30 participants who engaged with different versions of standard and interactive model cards. Through a thematic analysis of the collected data, we identified several conceptual dimensions that summarize the strengths and limitations of standard and interactive model cards, including: stakeholders; design; guidance; understandability & interpretability; sensemaking & skepticism; and trust & safety. Our findings demonstrate the importance of carefully considered design and interactivity for orienting and supporting non-expert analysts using deep learning models, along with a need for consideration of broader sociotechnical contexts and organizational dynamics. We have also identified design elements, such as language, visual cues, and warnings, among others, that support interactivity and make non-interactive content accessible. We summarize our findings as design guidelines and discuss their implications for a human-centered approach towards AI/ML documentation.

Recent strides in Large Language Models (LLMs) have saturated many NLP benchmarks (even professional domain-specific ones), emphasizing the need for novel, more challenging novel ones to properly assess LLM capabilities. In this paper, we introduce a novel NLP benchmark that poses challenges to current LLMs across four key dimensions: processing long documents (up to 50K tokens), utilizing domain specific knowledge (embodied in legal texts), multilingual understanding (covering five languages), and multitasking (comprising legal document to document Information Retrieval, Court View Generation, Leading Decision Summarization, Citation Extraction, and eight challenging Text Classification tasks). Our benchmark comprises diverse legal NLP datasets from the Swiss legal system, allowing for a comprehensive study of the underlying Non-English, inherently multilingual, federal legal system. Despite recent advances, efficiently processing long documents for intense review/analysis tasks remains an open challenge for language models. Also, comprehensive, domain-specific benchmarks requiring high expertise to develop are rare, as are multilingual benchmarks. This scarcity underscores our contribution's value, considering most public models are trained predominantly on English corpora, while other languages remain understudied, particularly for practical domain-specific NLP tasks. Our benchmark allows for testing and advancing the state-of-the-art LLMs. As part of our study, we evaluate several pre-trained multilingual language models on our benchmark to establish strong baselines as a point of reference. Despite the large size of our datasets (tens to hundreds of thousands of examples), existing publicly available models struggle with most tasks, even after in-domain pretraining. We publish all resources (benchmark suite, pre-trained models, code) under a fully permissive open CC BY-SA license.

Foundation models have made significant strides in various applications, including text-to-image generation, panoptic segmentation, and natural language processing. This paper presents Instruct2Act, a framework that utilizes Large Language Models to map multi-modal instructions to sequential actions for robotic manipulation tasks. Specifically, Instruct2Act employs the LLM model to generate Python programs that constitute a comprehensive perception, planning, and action loop for robotic tasks. In the perception section, pre-defined APIs are used to access multiple foundation models where the Segment Anything Model (SAM) accurately locates candidate objects, and CLIP classifies them. In this way, the framework leverages the expertise of foundation models and robotic abilities to convert complex high-level instructions into precise policy codes. Our approach is adjustable and flexible in accommodating various instruction modalities and input types and catering to specific task demands. We validated the practicality and efficiency of our approach by assessing it on robotic tasks in different scenarios within tabletop manipulation domains. Furthermore, our zero-shot method outperformed many state-of-the-art learning-based policies in several tasks. The code for our proposed approach is available at https://github.com/OpenGVLab/Instruct2Act, serving as a robust benchmark for high-level robotic instruction tasks with assorted modality inputs.

The objective of this study is to evaluate the potential for History Matching (HM) to tune a climate system with multi-scale dynamics. By considering a toy climate model, namely, the two-scale Lorenz96 model and producing experiments in perfect-model setting, we explore in detail how several built-in choices need to be carefully tested. We also demonstrate the importance of introducing physical expertise in the range of parameters, a priori to running HM. Finally we revisit a classical procedure in climate model tuning, that consists of tuning the slow and fast components separately. By doing so in the Lorenz96 model, we illustrate the non-uniqueness of plausible parameters and highlight the specificity of metrics emerging from the coupling. This paper contributes also to bridging the communities of uncertainty quantification, machine learning and climate modeling, by making connections between the terms used by each community for the same concept and presenting promising collaboration avenues that would benefit climate modeling research.

This paper provides a systematic analysis of the opportunities, challenges, and potential solutions of harnessing Large Language Models (LLMs) such as GPT-4 to dig out vulnerabilities within smart contracts based on our ongoing research. For the task of smart contract vulnerability detection, achieving practical usability hinges on identifying as many true vulnerabilities as possible while minimizing the number of false positives. Nonetheless, our empirical study reveals contradictory yet interesting findings: generating more answers with higher randomness largely boosts the likelihood of producing a correct answer but inevitably leads to a higher number of false positives. To mitigate this tension, we propose an adversarial framework dubbed GPTLens that breaks the conventional one-stage detection into two synergistic stages - generation and discrimination, for progressive detection and refinement, wherein the LLM plays dual roles, i.e., auditor and critic, respectively. The goal of auditor is to yield a broad spectrum of vulnerabilities with the hope of encompassing the correct answer, whereas the goal of critic that evaluates the validity of identified vulnerabilities is to minimize the number of false positives. Experimental results and illustrative examples demonstrate that auditor and critic work together harmoniously to yield pronounced improvements over the conventional one-stage detection. GPTLens is intuitive, strategic, and entirely LLM-driven without relying on specialist expertise in smart contracts, showcasing its methodical generality and potential to detect a broad spectrum of vulnerabilities. Our code is available at: https://github.com/git-disl/GPTLens.

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks due to the need for medical expertise in the responses. In response to this challenge, we propose HuaTuo, a LLaMA-based model that has been supervised-fine-tuned with generated QA (Question-Answer) instances. The experimental results demonstrate that HuaTuo generates responses that possess more reliable medical knowledge. Our proposed HuaTuo model is accessible at https://github.com/SCIR-HI/Huatuo-Llama-Med-Chinese.

Recent advances in large language models (LLMs) demonstrate substantial capabilities in natural language understanding and generation tasks. With the growing number of LLMs, how to harness the collective expertise of multiple LLMs is an exciting open direction. Toward this goal, we propose a new approach that leverages the collective strengths of multiple LLMs through a Mixture-of-Agents (MoA) methodology. In our approach, we construct a layered MoA architecture wherein each layer comprises multiple LLM agents. Each agent takes all the outputs from agents in the previous layer as auxiliary information in generating its response. MoA models achieves state-of-art performance on AlpacaEval 2.0, MT-Bench and FLASK, surpassing GPT-4 Omni. For example, our MoA using only open-source LLMs is the leader of AlpacaEval 2.0 by a substantial gap, achieving a score of 65.1% compared to 57.5% by GPT-4 Omni.

Interactive 3D simulated objects are crucial in AR/VR, animations, and robotics, driving immersive experiences and advanced automation. However, creating these articulated objects requires extensive human effort and expertise, limiting their broader applications. To overcome this challenge, we present Articulate-Anything, a system that automates the articulation of diverse, complex objects from many input modalities, including text, images, and videos. Articulate-Anything leverages vision-language models (VLMs) to generate code that can be compiled into an interactable digital twin for use in standard 3D simulators. Our system exploits existing 3D asset datasets via a mesh retrieval mechanism, along with an actor-critic system that iteratively proposes, evaluates, and refines solutions for articulating the objects, self-correcting errors to achieve a robust outcome. Qualitative evaluations demonstrate Articulate-Anything's capability to articulate complex and even ambiguous object affordances by leveraging rich grounded inputs. In extensive quantitative experiments on the standard PartNet-Mobility dataset, Articulate-Anything substantially outperforms prior work, increasing the success rate from 8.7-11.6% to 75% and setting a new bar for state-of-the-art performance. We further showcase the utility of our system by generating 3D assets from in-the-wild video inputs, which are then used to train robotic policies for fine-grained manipulation tasks in simulation that go beyond basic pick and place. These policies are then transferred to a real robotic system.

Large language models (LLMs) have demonstrated impressive results on natural language tasks, and security researchers are beginning to employ them in both offensive and defensive systems. In cyber-security, there have been multiple research efforts that utilize LLMs focusing on the pre-breach stage of attacks like phishing and malware generation. However, so far there lacks a comprehensive study regarding whether LLM-based systems can be leveraged to simulate the post-breach stage of attacks that are typically human-operated, or "hands-on-keyboard" attacks, under various attack techniques and environments. As LLMs inevitably advance, they may be able to automate both the pre- and post-breach attack stages. This shift may transform organizational attacks from rare, expert-led events to frequent, automated operations requiring no expertise and executed at automation speed and scale. This risks fundamentally changing global computer security and correspondingly causing substantial economic impacts, and a goal of this work is to better understand these risks now so we can better prepare for these inevitable ever-more-capable LLMs on the horizon. On the immediate impact side, this research serves three purposes. First, an automated LLM-based, post-breach exploitation framework can help analysts quickly test and continually improve their organization's network security posture against previously unseen attacks. Second, an LLM-based penetration test system can extend the effectiveness of red teams with a limited number of human analysts. Finally, this research can help defensive systems and teams learn to detect novel attack behaviors preemptively before their use in the wild....

Communication system formulation is critical for advancing 6G and future wireless technologies, yet it remains a complex, expertise-intensive task. While Large Language Models (LLMs) offer potential, existing general-purpose models often lack the specialized domain knowledge, nuanced reasoning capabilities, and access to high-quality, domain-specific training data required for adapting a general LLM into an LLM specially for communication system formulation. To bridge this gap, we introduce DeepForm, the first reasoning LLM specially for automated communication system formulation. We propose the world-first large-scale, open-source dataset meticulously curated for this domain called Communication System Formulation Reasoning Corpus (CSFRC). Our framework employs a two-stage training strategy: first, Supervised Fine-Tuning (SFT) with Chain-of-Thought (CoT) data to distill domain knowledge; second, a novel rule-based Reinforcement Learning (RL) algorithm, C-ReMax based on ReMax, to cultivate advanced modeling capabilities and elicit sophisticated reasoning patterns like self-correction and verification. Extensive experiments demonstrate that our model achieves state-of-the-art performance, significantly outperforming larger proprietary LLMs on diverse senerios. We will release related resources to foster further research in this area after the paper is accepted.

Interpreting computed tomography (CT) requires review of hundreds of volumetric slices and remains time-intensive and expertise-dependent. Automated CT report generation offers a promising route to improving clinical efficiency, yet the field still lacks a generalizable CT report generation foundation model that supports multi-region reporting and remains robust across external real-world cohorts. Intrinsic inconsistencies in reporting style and diagnostic terminology across cohorts make naive joint training difficult. Here we present Astra, a generalizable CT report generation foundation model developed on 90,678 thoracoabdominal CT-report pairs collected from five sites worldwide (CTRgDB), comprising 353,671 abnormalities spanning eight organ systems. By harmonizing report style and further refining diagnostic consistency via reinforcement learning, Astra achieves style-consistent and diagnostically accurate report generation across diverse anatomical regions and institutions. Evaluated on CTRgDB and six external cohorts, Astra achieves state-of-the-art performance with a 38.4% average improvement in fine-grained diagnostic metrics (P<0.001). Deployed at external clinical sites without any site-specific fine-tuning, Astra accelerated chest report drafting by 29.6% and improved abdominal report completeness by 11.3% among junior and mid-level radiologists (P<0.001). Furthermore, Astra demonstrates broad utility as a foundation for CT AI development, improving downstream diagnostic performance and scaling vision-language pretrain through high-quality report synthesis. Overall, Astra serves as a broadly accessible clinical assistant and a pivotal infrastructure for the next generation of AI-powered healthcare. The code for Astra is publicly available at https://github.com/zh-Wang-Med/Astra.

A transformer can make an attribute linearly decodable in its residual stream at a depth where that attribute does not yet influence the output. This gap between where information is readable and where it is used has been shown for attributes stated directly in the input. We ask whether it also holds for an attribute the model must infer gradually over a conversation, namely how expert its dialogue partner is. Using ExpertCollab, a corpus of multi-turn research-planning dialogues between model-played personas at four expertise levels, we find that partner expertise is most decodable in the early layers and falls to near chance before the midpoint of the network. Counterfactual patching shows that injecting the expertise difference at the layer of peak decodability barely changes a fixed late-layer readout, whereas the same difference injected past the midpoint propagates almost completely, a separation of more than an order of magnitude. A content-matched random control and a probe-free diagnostic place the transition at the same early layer, and a statically specified control attribute stays decodable throughout. An inferred relational attribute is therefore represented well before it becomes causally active, which bounds where any attempt to read out or steer partner-conditioned behavior must intervene. We use one model on a synthetic corpus as an initial demonstration.

3D graphics editing is crucial in applications like movie production and game design, yet it remains a time-consuming process that demands highly specialized domain expertise. Automating this process is challenging because graphical editing requires performing a variety of tasks, each requiring distinct skill sets. Recently, vision-language models (VLMs) have emerged as a powerful framework for automating the editing process, but their development and evaluation are bottlenecked by the lack of a comprehensive benchmark that requires human-level perception and presents real-world editing complexity. In this work, we present BlenderGym, the first comprehensive VLM system benchmark for 3D graphics editing. BlenderGym evaluates VLM systems through code-based 3D reconstruction tasks. We evaluate closed- and open-source VLM systems and observe that even the state-of-the-art VLM system struggles with tasks relatively easy for human Blender users. Enabled by BlenderGym, we study how inference scaling techniques impact VLM's performance on graphics editing tasks. Notably, our findings reveal that the verifier used to guide the scaling of generation can itself be improved through inference scaling, complementing recent insights on inference scaling of LLM generation in coding and math tasks. We further show that inference compute is not uniformly effective and can be optimized by strategically distributing it between generation and verification.

Although artificial intelligence (AI) has made significant progress in understanding molecules in a wide range of fields, existing models generally acquire the single cognitive ability from the single molecular modality. Since the hierarchy of molecular knowledge is profound, even humans learn from different modalities including both intuitive diagrams and professional texts to assist their understanding. Inspired by this, we propose a molecular multimodal foundation model which is pretrained from molecular graphs and their semantically related textual data (crawled from published Scientific Citation Index papers) via contrastive learning. This AI model represents a critical attempt that directly bridges molecular graphs and natural language. Importantly, through capturing the specific and complementary information of the two modalities, our proposed model can better grasp molecular expertise. Experimental results show that our model not only exhibits promising performance in cross-modal tasks such as cross-modal retrieval and molecule caption, but also enhances molecular property prediction and possesses capability to generate meaningful molecular graphs from natural language descriptions. We believe that our model would have a broad impact on AI-empowered fields across disciplines such as biology, chemistry, materials, environment, and medicine, among others.

Model merging aims to consolidate multiple task-specific models fine-tuned on different datasets into a unified architecture that performs cross-domain proficiency. Current data-free model merging methods often struggle to scale as they rely on simple parameter-level heuristics that ignore inter-layer dependencies and non-uniform distribution of expertise. This work proposes SA-Merging, which is built upon connectivity-based saliency formulations from structural pruning (e.g., SynFlow) and extends them to the data-free model merging setting. We define a saliency score over task vectors relative to a shared base model, and further introduce merge-aware modulation that incorporates agreement across experts to mitigate task interference. Based on this formulation, an iterative saliency-aware merging procedure progressively removes non-informative updates while preserving end-to-end connectivity. Furthermore, we extend SA-Merging to introduce rank-wise saliency decomposition for LoRAs without compromising their structural integrity. Extensive experiments on vision and language tasks demonstrate the effectiveness of our saliency-based approach, further reducing the gap between data-free and test-time adaptation methods.

Histopathological examination primarily relies on hematoxylin and eosin (H&E) and immunohistochemistry (IHC) staining. Although IHC provides critical molecular information, it is costly and requires specialized expertise. Stain transfer provides an efficient alternative by computationally generating IHC from H&E images, but remains challenged by unified and interpretable modeling for heterogeneous biomarkers under pixel-unaligned supervision. We propose DMCoStain, a novel Data-Model Co-optimization framework for Stain transfer. It iteratively co-refines training data and model capability, improving staining accuracy and interpretability in both pathological and structural consistency. To refine training data in a clinically meaningful manner, it incorporates the Multimodal Expert-Guided Finer Selection (MEGFS) strategy, built upon a pioneering IHC-positive-expression (IPE) vision-language model (VLM) that emulates pathologist reasoning. To support MEGFS, we construct ImmunoInstruction, the first large-scale IPE instruction-following dataset with 150K VQA samples. Extensive experiments on multiple tissues and biomarkers demonstrate that DMCoStain achieves state-of-the-art (SOTA) accuracy. This paradigm offers strong practical value, and MEGFS also functions as a specialized evaluation tool for future model development. Dataset, code, and more details are in https://github.com/SikangSHU/DMCoStain.

Natural Language Processing (NLP) has recently gained wide attention in cybersecurity, particularly in Cyber Threat Intelligence (CTI) and cyber automation. Increased connection and automation have revolutionized the world's economic and cultural infrastructures, while they have introduced risks in terms of cyber attacks. CTI is information that helps cybersecurity analysts make intelligent security decisions, that is often delivered in the form of natural language text, which must be transformed to machine readable format through an automated procedure before it can be used for automated security measures. This paper proposes SecureBERT, a cybersecurity language model capable of capturing text connotations in cybersecurity text (e.g., CTI) and therefore successful in automation for many critical cybersecurity tasks that would otherwise rely on human expertise and time-consuming manual efforts. SecureBERT has been trained using a large corpus of cybersecurity text.To make SecureBERT effective not just in retaining general English understanding, but also when applied to text with cybersecurity implications, we developed a customized tokenizer as well as a method to alter pre-trained weights. The SecureBERT is evaluated using the standard Masked Language Model (MLM) test as well as two additional standard NLP tasks. Our evaluation studies show that SecureBERT\url{https://github.com/ehsanaghaei/SecureBERT} outperforms existing similar models, confirming its capability for solving crucial NLP tasks in cybersecurity.

Large Language Models (LLMs) have exhibited remarkable capabilities in understanding and interacting with natural language across various sectors. However, their effectiveness is limited in specialized areas requiring high accuracy, such as plant science, due to a lack of specific expertise in these fields. This paper introduces PLLaMa, an open-source language model that evolved from LLaMa-2. It's enhanced with a comprehensive database, comprising more than 1.5 million scholarly articles in plant science. This development significantly enriches PLLaMa with extensive knowledge and proficiency in plant and agricultural sciences. Our initial tests, involving specific datasets related to plants and agriculture, show that PLLaMa substantially improves its understanding of plant science-related topics. Moreover, we have formed an international panel of professionals, including plant scientists, agricultural engineers, and plant breeders. This team plays a crucial role in verifying the accuracy of PLLaMa's responses to various academic inquiries, ensuring its effective and reliable application in the field. To support further research and development, we have made the model's checkpoints and source codes accessible to the scientific community. These resources are available for download at https://github.com/Xianjun-Yang/PLLaMa.

Recent advances in Large Language Models (LLMs) have achieved remarkable breakthroughs in understanding and responding to user intents. However, their performance lag behind general use cases in some expertise domains, such as Chinese medicine. Existing efforts to incorporate Chinese medicine into LLMs rely on Supervised Fine-Tuning (SFT) with single-turn and distilled dialogue data. These models lack the ability for doctor-like proactive inquiry and multi-turn comprehension and cannot align responses with experts' intentions. In this work, we introduce Zhongjing, the first Chinese medical LLaMA-based LLM that implements an entire training pipeline from continuous pre-training, SFT, to Reinforcement Learning from Human Feedback (RLHF). Additionally, we construct a Chinese multi-turn medical dialogue dataset of 70,000 authentic doctor-patient dialogues, CMtMedQA, which significantly enhances the model's capability for complex dialogue and proactive inquiry initiation. We also define a refined annotation rule and evaluation criteria given the unique characteristics of the biomedical domain. Extensive experimental results show that Zhongjing outperforms baselines in various capacities and matches the performance of ChatGPT in some abilities, despite the 100x parameters. Ablation studies also demonstrate the contributions of each component: pre-training enhances medical knowledge, and RLHF further improves instruction-following ability and safety. Our code, datasets, and models are available at https://github.com/SupritYoung/Zhongjing.

Multimodal Language Language Models (MLLMs) demonstrate the emerging abilities of "world models" -- interpreting and reasoning about complex real-world dynamics. To assess these abilities, we posit videos are the ideal medium, as they encapsulate rich representations of real-world dynamics and causalities. To this end, we introduce MMWorld, a new benchmark for multi-discipline, multi-faceted multimodal video understanding. MMWorld distinguishes itself from previous video understanding benchmarks with two unique advantages: (1) multi-discipline, covering various disciplines that often require domain expertise for comprehensive understanding; (2) multi-faceted reasoning, including explanation, counterfactual thinking, future prediction, etc. MMWorld consists of a human-annotated dataset to evaluate MLLMs with questions about the whole videos and a synthetic dataset to analyze MLLMs within a single modality of perception. Together, MMWorld encompasses 1,910 videos across seven broad disciplines and 69 subdisciplines, complete with 6,627 question-answer pairs and associated captions. The evaluation includes 2 proprietary and 10 open-source MLLMs, which struggle on MMWorld (e.g., GPT-4V performs the best with only 52.3\% accuracy), showing large room for improvement. Further ablation studies reveal other interesting findings such as models' different skill sets from humans. We hope MMWorld can serve as an essential step towards world model evaluation in videos.

In the realm of digital creativity, our potential to craft intricate 3D worlds from imagination is often hampered by the limitations of existing digital tools, which demand extensive expertise and efforts. To narrow this disparity, we introduce CLAY, a 3D geometry and material generator designed to effortlessly transform human imagination into intricate 3D digital structures. CLAY supports classic text or image inputs as well as 3D-aware controls from diverse primitives (multi-view images, voxels, bounding boxes, point clouds, implicit representations, etc). At its core is a large-scale generative model composed of a multi-resolution Variational Autoencoder (VAE) and a minimalistic latent Diffusion Transformer (DiT), to extract rich 3D priors directly from a diverse range of 3D geometries. Specifically, it adopts neural fields to represent continuous and complete surfaces and uses a geometry generative module with pure transformer blocks in latent space. We present a progressive training scheme to train CLAY on an ultra large 3D model dataset obtained through a carefully designed processing pipeline, resulting in a 3D native geometry generator with 1.5 billion parameters. For appearance generation, CLAY sets out to produce physically-based rendering (PBR) textures by employing a multi-view material diffusion model that can generate 2K resolution textures with diffuse, roughness, and metallic modalities. We demonstrate using CLAY for a range of controllable 3D asset creations, from sketchy conceptual designs to production ready assets with intricate details. Even first time users can easily use CLAY to bring their vivid 3D imaginations to life, unleashing unlimited creativity.

While large language models (LLMs) have showcased impressive capabilities, they struggle with addressing legal queries due to the intricate complexities and specialized expertise required in the legal field. In this paper, we introduce InternLM-Law, a specialized LLM tailored for addressing diverse legal queries related to Chinese laws, spanning from responding to standard legal questions (e.g., legal exercises in textbooks) to analyzing complex real-world legal situations. We meticulously construct a dataset in the Chinese legal domain, encompassing over 1 million queries, and implement a data filtering and processing pipeline to ensure its diversity and quality. Our training approach involves a novel two-stage process: initially fine-tuning LLMs on both legal-specific and general-purpose content to equip the models with broad knowledge, followed by exclusive fine-tuning on high-quality legal data to enhance structured output generation. InternLM-Law achieves the highest average performance on LawBench, outperforming state-of-the-art models, including GPT-4, on 13 out of 20 subtasks. We make InternLM-Law and our dataset publicly available to facilitate future research in applying LLMs within the legal domain.

Leveraging multiple large language model (LLM) agents has shown to be a promising approach for tackling complex tasks, while the effective design of multiple agents for a particular application remains an art. It is thus intriguing to answer a critical question: Given a task, how can we build a team of LLM agents to solve it effectively? Our new adaptive team-building paradigm offers a flexible solution, realized through a novel agent design named Captain Agent. It dynamically forms and manages teams for each step of a task-solving process, utilizing nested group conversations and reflection to ensure diverse expertise and prevent stereotypical outputs. It allows for a flexible yet structured approach to problem-solving and can help reduce redundancy and enhance output diversity. A comprehensive evaluation across six real-world scenarios demonstrates that Captain Agent significantly outperforms existing multi-agent methods with 21.94% improvement in average accuracy, providing outstanding performance without requiring task-specific prompt engineering.

Generative AI, particularly Language Models (LMs), has the potential to transform real-world domains with societal impact, particularly where access to experts is limited. For example, in education, training novice educators with expert guidance is important for effectiveness but expensive, creating significant barriers to improving education quality at scale. This challenge disproportionately harms students from under-served communities, who stand to gain the most from high-quality education. We introduce Tutor CoPilot, a novel Human-AI approach that leverages a model of expert thinking to provide expert-like guidance to tutors as they tutor. This study is the first randomized controlled trial of a Human-AI system in live tutoring, involving 900 tutors and 1,800 K-12 students from historically under-served communities. Following a preregistered analysis plan, we find that students working with tutors that have access to Tutor CoPilot are 4 percentage points (p.p.) more likely to master topics (p<0.01). Notably, students of lower-rated tutors experienced the greatest benefit, improving mastery by 9 p.p. We find that Tutor CoPilot costs only $20 per-tutor annually. We analyze 550,000+ messages using classifiers to identify pedagogical strategies, and find that tutors with access to Tutor CoPilot are more likely to use high-quality strategies to foster student understanding (e.g., asking guiding questions) and less likely to give away the answer to the student. Tutor interviews highlight how Tutor CoPilot's guidance helps tutors to respond to student needs, though they flag issues in Tutor CoPilot, such as generating suggestions that are not grade-level appropriate. Altogether, our study of Tutor CoPilot demonstrates how Human-AI systems can scale expertise in real-world domains, bridge gaps in skills and create a future where high-quality education is accessible to all students.

Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount significance in facilitating biomedical research. However, existing multimodal molecular foundation models exhibit limitations in capturing intricate connections between molecular structures and texts, and more importantly, none of them attempt to leverage a wealth of molecular expertise derived from knowledge graphs. In this study, we introduce MolFM, a multimodal molecular foundation model designed to facilitate joint representation learning from molecular structures, biomedical texts, and knowledge graphs. We propose cross-modal attention between atoms of molecular structures, neighbors of molecule entities and semantically related texts to facilitate cross-modal comprehension. We provide theoretical analysis that our cross-modal pre-training captures local and global molecular knowledge by minimizing the distance in the feature space between different modalities of the same molecule, as well as molecules sharing similar structures or functions. MolFM achieves state-of-the-art performance on various downstream tasks. On cross-modal retrieval, MolFM outperforms existing models with 12.13% and 5.04% absolute gains under the zero-shot and fine-tuning settings, respectively. Furthermore, qualitative analysis showcases MolFM's implicit ability to provide grounding from molecular substructures and knowledge graphs. Code and models are available on https://github.com/BioFM/OpenBioMed.

Large Language Models (LLMs) exhibit considerable promise in financial applications; however, prevailing models frequently demonstrate limitations when confronted with scenarios that necessitate sophisticated reasoning capabilities, stringent trustworthiness criteria, and efficient adaptation to domain-specific requirements. We introduce the Agentar-Fin-R1 series of financial large language models (8B and 32B parameters), specifically engineered based on the Qwen3 foundation model to enhance reasoning capabilities, reliability, and domain specialization for financial applications. Our optimization approach integrates a high-quality, systematic financial task label system with a comprehensive multi-layered trustworthiness assurance framework. This framework encompasses high-quality trustworthy knowledge engineering, multi-agent trustworthy data synthesis, and rigorous data validation governance. Through label-guided automated difficulty-aware optimization, tow-stage training pipeline, and dynamic attribution systems, we achieve substantial improvements in training efficiency. Our models undergo comprehensive evaluation on mainstream financial benchmarks including Fineva, FinEval, and FinanceIQ, as well as general reasoning datasets such as MATH-500 and GPQA-diamond. To thoroughly assess real-world deployment capabilities, we innovatively propose the Finova evaluation benchmark, which focuses on agent-level financial reasoning and compliance verification. Experimental results demonstrate that Agentar-Fin-R1 not only achieves state-of-the-art performance on financial tasks but also exhibits exceptional general reasoning capabilities, validating its effectiveness as a trustworthy solution for high-stakes financial applications. The Finova bench is available at https://github.com/antgroup/Finova.

In recent years, a plethora of open-source foundation models have emerged, achieving remarkable progress in some widely attended fields, with performance being quite close to that of closed-source models. However, in high-value but more challenging scientific professional fields, either the fields still rely on expert models, or the progress of general foundation models lags significantly compared to those in popular areas, far from sufficient for transforming scientific research and leaving substantial gap between open-source models and closed-source models in these scientific domains. To mitigate this gap and explore a step further toward Artificial General Intelligence (AGI), we introduce Intern-S1, a specialized generalist equipped with general understanding and reasoning capabilities with expertise to analyze multiple science modal data. Intern-S1 is a multimodal Mixture-of-Experts (MoE) model with 28 billion activated parameters and 241 billion total parameters, continually pre-trained on 5T tokens, including over 2.5T tokens from scientific domains. In the post-training stage, Intern-S1 undergoes offline and then online reinforcement learning (RL) in InternBootCamp, where we propose Mixture-of-Rewards (MoR) to synergize the RL training on more than 1000 tasks simultaneously. Through integrated innovations in algorithms, data, and training systems, Intern-S1 achieved top-tier performance in online RL training.On comprehensive evaluation benchmarks, Intern-S1 demonstrates competitive performance on general reasoning tasks among open-source models and significantly outperforms open-source models in scientific domains, surpassing closed-source state-of-the-art models in professional tasks, such as molecular synthesis planning, reaction condition prediction, predicting thermodynamic stabilities for crystals. Our models are available at https://huggingface.co/internlm/Intern-S1.

Prompt learning has surfaced as an effective approach to enhance the performance of Vision-Language Models (VLMs) like CLIP when applied to downstream tasks. However, current learnable prompt tokens are primarily used for the single phase of adapting to tasks (i.e., adapting prompt), easily leading to overfitting risks. In this work, we propose a novel Cascade Prompt Learning CasPL framework to enable prompt learning to serve both generic and specific expertise (i.e., boosting and adapting prompt) simultaneously. Specifically, CasPL is a new learning paradigm comprising two distinct phases of learnable prompts: the first boosting prompt is crafted to extract domain-general knowledge from a senior larger CLIP teacher model by aligning their predicted logits using extensive unlabeled domain images. The second adapting prompt is then cascaded with the frozen first set to fine-tune the downstream tasks, following the approaches employed in prior research. In this manner, CasPL can effectively capture both domain-general and task-specific representations into explicitly different gradual groups of prompts, thus potentially alleviating overfitting issues in the target domain. It's worth noting that CasPL serves as a plug-and-play module that can seamlessly integrate into any existing prompt learning approach. CasPL achieves a significantly better balance between performance and inference speed, which is especially beneficial for deploying smaller VLM models in resource-constrained environments. Compared to the previous state-of-the-art method PromptSRC, CasPL shows an average improvement of 1.85% for base classes, 3.44% for novel classes, and 2.72% for the harmonic mean over 11 image classification datasets. Code is publicly available at: https://github.com/megvii-research/CasPL.

Large language models have demonstrated remarkable reasoning capabilities across diverse natural language tasks. However, comparable breakthroughs in scientific discovery are more limited, because understanding complex physical phenomena demands multifaceted representations far beyond language alone. A compelling example is the design of functional materials such as MOFs-critical for a range of impactful applications like carbon capture and hydrogen storage. Navigating their vast and intricate design space in language-based representations interpretable by LLMs is challenging due to the numerous possible three-dimensional atomic arrangements and strict reticular rules of coordination geometry and topology. Despite promising early results in LLM-assisted discovery for simpler materials systems, MOF design remains heavily reliant on tacit human expertise rarely codified in textual information alone. To overcome this barrier, we introduce L2M3OF, the first multimodal LLM for MOFs. L2M3OF integrates crystal representation learning with language understanding to process structural, textual, and knowledge modalities jointly. L2M3OF employs a pre-trained crystal encoder with a lightweight projection layer to compress structural information into a token space, enabling efficient alignment with language instructions. To facilitate training and evaluation, we curate a structure-property-knowledge database of crystalline materials and benchmark L2M3OF against state-of-the-art closed-source LLMs such as GPT-5, Gemini-2.5-Pro and DeepSeek-R1. Experiments show that L2M3OF outperforms leading text-based closed-source LLMs in property prediction and knowledge generation tasks, despite using far fewer parameters. These results highlight the importance of multimodal approaches for porous material understanding and establish L2M3OF as a foundation for next-generation AI systems in materials discovery.

The deployment of Multimodal Large Language Models (MLLMs) in agriculture is currently stalled by a critical trade-off: the existing literature lacks the large-scale agricultural datasets required for robust model development and evaluation, while current state-of-the-art models lack the verified domain expertise necessary to reason across diverse taxonomies. To address these challenges, we propose the Vision-to-Verified-Knowledge (V2VK) pipeline, a novel generative AI-driven annotation framework that integrates visual captioning with web-augmented scientific retrieval to autonomously generate the AgriMM benchmark, effectively eliminating biological hallucinations by grounding training data in verified phytopathological literature. The AgriMM benchmark contains over 3,000 agricultural classes and more than 607k VQAs spanning multiple tasks, including fine-grained plant species identification, plant disease symptom recognition, crop counting, and ripeness assessment. Leveraging this verifiable data, we present AgriChat, a specialized MLLM that presents broad knowledge across thousands of agricultural classes and provides detailed agricultural assessments with extensive explanations. Extensive evaluation across diverse tasks, datasets, and evaluation conditions reveals both the capabilities and limitations of current agricultural MLLMs, while demonstrating AgriChat's superior performance over other open-source models, including internal and external benchmarks. The results validate that preserving visual detail combined with web-verified knowledge constitutes a reliable pathway toward robust and trustworthy agricultural AI. The code and dataset are publicly available at https://github.com/boudiafA/AgriChat .

Multimodal Large Language Models have demonstrated powerful cross-modal understanding and reasoning capabilities in general domains. However, in the electromagnetic (EM) domain, they still face challenges such as data scarcity and insufficient integration of domain knowledge. This paper proposes PReD, the first foundation model for the EM domain that covers the intelligent closed-loop of "perception, recognition, decision-making." We constructed a high-quality multitask EM dataset, PReD-1.3M, and an evaluation benchmark, PReD-Bench. The dataset encompasses multi-perspective representations such as raw time-domain waveform, frequency-domain spectrograms, and constellation diagrams, covering typical features of communication and radar signals. It supports a range of core tasks, including signal detection, modulation recognition, parameter estimation, protocol recognition, radio frequency fingerprint recognition, and anti-jamming decision-making. PReD adopts a multi-stage training strategy that unifies multiple tasks for EM signals. It achieves closed-loop optimization from end-to-end signal understanding to language-driven reasoning and decision-making, significantly enhancing EM domain expertise while maintaining general multimodal capabilities. Experimental results show that PReD achieves state-of-the-art performance on PReD-Bench constructed from both open-source and self-collected signal datasets. These results collectively validate the feasibility and potential of vision-aligned foundation models in advancing the understanding and reasoning of EM signals.

Musculoskeletal disorders represent a significant global health burden and are a leading cause of disability worldwide. While MRI is essential for accurate diagnosis, its interpretation remains exceptionally challenging. Radiologists must identify multiple potential abnormalities within complex anatomical structures across different imaging planes, a process that requires significant expertise and is prone to variability. We developed OrthoDiffusion, a unified diffusion-based foundation model designed for multi-task musculoskeletal MRI interpretation. The framework utilizes three orientation-specific 3D diffusion models, pre-trained in a self-supervised manner on 15,948 unlabeled knee MRI scans, to learn robust anatomical features from sagittal, coronal, and axial views. These view-specific representations are integrated to support diverse clinical tasks, including anatomical segmentation and multi-label diagnosis. Our evaluation demonstrates that OrthoDiffusion achieves excellent performance in the segmentation of 11 knee structures and the detection of 8 knee abnormalities. The model exhibited remarkable robustness across different clinical centers and MRI field strengths, consistently outperforming traditional supervised models. Notably, in settings where labeled data was scarce, OrthoDiffusion maintained high diagnostic precision using only 10\% of training labels. Furthermore, the anatomical representations learned from knee imaging proved highly transferable to other joints, achieving strong diagnostic performance across 11 diseases of the ankle and shoulder. These findings suggest that diffusion-based foundation models can serve as a unified platform for multi-disease diagnosis and anatomical segmentation, potentially improving the efficiency and accuracy of musculoskeletal MRI interpretation in real-world clinical workflows.

Diagnosing and managing oral diseases necessitate advanced visual interpretation across diverse imaging modalities and integrated information synthesis. While current AI models excel at isolated tasks, they often fall short in addressing the complex, multimodal requirements of comprehensive clinical dental practice. Here we introduce DentVLM, a multimodal vision-language model engineered for expert-level oral disease diagnosis. DentVLM was developed using a comprehensive, large-scale, bilingual dataset of 110,447 images and 2.46 million visual question-answering (VQA) pairs. The model is capable of interpreting seven 2D oral imaging modalities across 36 diagnostic tasks, significantly outperforming leading proprietary and open-source models by 19.6% higher accuracy for oral diseases and 27.9% for malocclusions. In a clinical study involving 25 dentists, evaluating 1,946 patients and encompassing 3,105 QA pairs, DentVLM surpassed the diagnostic performance of 13 junior dentists on 21 of 36 tasks and exceeded that of 12 senior dentists on 12 of 36 tasks. When integrated into a collaborative workflow, DentVLM elevated junior dentists' performance to senior levels and reduced diagnostic time for all practitioners by 15-22%. Furthermore, DentVLM exhibited promising performance across three practical utility scenarios, including home-based dental health management, hospital-based intelligent diagnosis and multi-agent collaborative interaction. These findings establish DentVLM as a robust clinical decision support tool, poised to enhance primary dental care, mitigate provider-patient imbalances, and democratize access to specialized medical expertise within the field of dentistry.

Foundation models are reshaping computational pathology, yet their capabilities remain shaped by pretraining objectives, data sources, and spatial scales, fragmenting complementary expertise across separate backbones. Here we present ALICE, a unified foundation model trained through multi-stage agglomerative distillation that sequentially distills eight vision-only, vision-language, and slide-level teacher models into dedicated modules of a single backbone. ALICE is pretrained on 24,985,184 tile-level pathology images and 155,604 high-resolution images, and evaluated across 21 task scenarios, 96 downstream tasks, and 48 data sources, spanning region-of-interest tissue analysis, vision-language multimodal evaluation, and whole-slide clinical assessment. In all three evaluation settings, ALICE achieved the best average rank among task-matched pathology foundation models. These results demonstrate that agglomerative distillation can consolidate complementary capabilities from specialized models into a unified backbone for broad computational pathology applications. The model is available at https://github.com/WonderLandxD/ALICE.

Road traffic injuries remain a major challenge in low- and middle-income countries, where proactive road safety auditing is limited by incomplete crash records, shortages of qualified auditors, and the high cost of large-scale field inspections. To address this problem, we propose Expert-Grounded Distillation (EGD), a novel artificial intelligence framework that transfers institutional road safety expertise into a compact vision-language model for scalable visual road safety auditing. The key innovation is a quantified expert-grounding stage in which the teacher vision-language model is calibrated against authoritative field audits. Large-scale annotation is permitted only after the teacher reaches substantial agreement with expert risk assessments (Cohen's kappa = 0.74). The calibrated teacher then generates structured supervision that is distilled into an 8-billion-parameter student vision-language model using Low-Rank Adaptation and a single leakage-free prompt. We also introduce Bangladesh Road Safety Audit (BD-ARSA), the first open, expert-grounded Bangladeshi visual road safety audit dataset containing 21,947 image-audit records with near-national coverage, and Expert-Grounded Road Safety Auditor (EG-ARSA), the first vision-language model developed specifically for this task. Experimental results show that grounded fine-tuning substantially improves ordinal risk assessment over the zero-shot baseline, while blind expert evaluation demonstrates that the compact student outperforms both its 31 billion-parameter teacher and Gemini-2.5-Flash. These findings demonstrate that EGD provides an effective and scalable engineering solution for proactive road safety auditing in resource-constrained environments.

The rapid proliferation of large language models (LLMs) and the growing diversity of their applications presents a unique optimization opportunity: selecting the right model for the task, while optimizing for speed, cost, and quality at a per-task level. However, inference endpoints can vary widely in quality, price, latency, context support, tool use, domain expertise, and reasoning behavior. This heterogeneity makes manual heuristics difficult to maintain and unlikely to achieve consistently favorable speed--cost--quality trade-offs on their own. We introduce , a lightweight GLiClass-based router that assigns a suitability score to each inference-time model label without autoregressive generation. The released 0.6B-parameter checkpoint combines a Qwen3 decoder with a shallow bidirectional scorer. Its decoder-KV execution path preserves a text-only key--value cache across a session, encodes only new dialogue turns, and evaluates transient candidate-label tokens without adding them to the persistent cache. The same checkpoint also predicts task type, difficulty, reasoning mode, and expected output length, and supports custom zero-shot labels. For task generation, we construct a task ontology with 23 families, 115 task types, 345 routable subtypes, 1,173 synthetic examples, and an orthogonal axis of 30 domains. Using this structure, we generate 150,000 verifier-scored tasks and 15,000 open-ended tasks. We then train the Qwen3 decoder on these tasks, while explicitly separating learned request prediction from per-task policies for attributes such as eligibility, cost, cache reuse, safety, and sovereignty. Across six LiveBench subsets, the router outperforms the mean candidate; on the selected 1,000-task subset, it achieves an aggregate top-1 score of 0.707 versus 0.696 for the strongest fixed model, with benchmark-dependent gains.

This study proposes the design and implementation of a multimodal LLM-based Multi-Agent System (MAS) leveraging a No-Code platform to address the practical constraints and significant entry barriers associated with AI adoption in enterprises. Advanced AI technologies, such as Large Language Models (LLMs), often pose challenges due to their technical complexity and high implementation costs, making them difficult for many organizations to adopt. To overcome these limitations, this research develops a No-Code-based Multi-Agent System designed to enable users without programming knowledge to easily build and manage AI systems. The study examines various use cases to validate the applicability of AI in business processes, including code generation from image-based notes, Advanced RAG-based question-answering systems, text-based image generation, and video generation using images and prompts. These systems lower the barriers to AI adoption, empowering not only professional developers but also general users to harness AI for significantly improved productivity and efficiency. By demonstrating the scalability and accessibility of No-Code platforms, this study advances the democratization of AI technologies within enterprises and validates the practical applicability of Multi-Agent Systems, ultimately contributing to the widespread adoption of AI across various industries.

With the growing applications of Deep Learning (DL), especially recent spectacular achievements of Large Language Models (LLMs) such as ChatGPT and LLaMA, the commercial significance of these remarkable models has soared. However, acquiring well-trained models is costly and resource-intensive. It requires a considerable high-quality dataset, substantial investment in dedicated architecture design, expensive computational resources, and efforts to develop technical expertise. Consequently, safeguarding the Intellectual Property (IP) of well-trained models is attracting increasing attention. In contrast to existing surveys overwhelmingly focusing on model IPP mainly, this survey not only encompasses the protection on model level intelligence but also valuable dataset intelligence. Firstly, according to the requirements for effective IPP design, this work systematically summarizes the general and scheme-specific performance evaluation metrics. Secondly, from proactive IP infringement prevention and reactive IP ownership verification perspectives, it comprehensively investigates and analyzes the existing IPP methods for both dataset and model intelligence. Additionally, from the standpoint of training settings, it delves into the unique challenges that distributed settings pose to IPP compared to centralized settings. Furthermore, this work examines various attacks faced by deep IPP techniques. Finally, we outline prospects for promising future directions that may act as a guide for innovative research.

Ensuring compliance with international data protection standards for privacy and data security is a crucial but complex task, often requiring substantial legal expertise. This paper introduces LegiLM, a novel legal language model specifically tailored for consulting on data or information compliance. LegiLM leverages a pre-trained GDPR Fines dataset and has been fine-tuned to automatically assess whether particular actions or events breach data security and privacy regulations. By incorporating a specialized dataset that includes global data protection laws, meticulously annotated policy documents, and relevant privacy policies, LegiLM is optimized for addressing data compliance challenges. The model integrates advanced legal reasoning methods and information retrieval enhancements to enhance accuracy and reliability in practical legal consulting scenarios. Our evaluation using a custom benchmark dataset demonstrates that LegiLM excels in detecting data regulation breaches, offering sound legal justifications, and recommending necessary compliance modifications, setting a new benchmark for AI-driven legal compliance solutions. Our resources are publicly available at https://github.com/DAOLegalAI/LegiLM

Natural language descriptions of optimization or satisfaction problems are challenging to translate into correct MiniZinc models, as this process demands both logical reasoning and constraint programming expertise. We introduce Gala, a framework that addresses this challenge with a global agentic approach: multiple specialized large language model (LLM) agents decompose the modeling task by global constraint type. Each agent is dedicated to detecting and generating code for a specific class of global constraint, while a final assembler agent integrates these constraint snippets into a complete MiniZinc model. By dividing the problem into smaller, well-defined sub-tasks, each LLM handles a simpler reasoning challenge, potentially reducing overall complexity. We conduct initial experiments with several LLMs and show better performance against baselines such as one-shot prompting and chain-of-thought prompting. Finally, we outline a comprehensive roadmap for future work, highlighting potential enhancements and directions for improvement.

In recent years, data science agents powered by Large Language Models (LLMs), known as "data agents," have shown significant potential to transform the traditional data analysis paradigm. This survey provides an overview of the evolution, capabilities, and applications of LLM-based data agents, highlighting their role in simplifying complex data tasks and lowering the entry barrier for users without related expertise. We explore current trends in the design of LLM-based frameworks, detailing essential features such as planning, reasoning, reflection, multi-agent collaboration, user interface, knowledge integration, and system design, which enable agents to address data-centric problems with minimal human intervention. Furthermore, we analyze several case studies to demonstrate the practical applications of various data agents in real-world scenarios. Finally, we identify key challenges and propose future research directions to advance the development of data agents into intelligent statistical analysis software.

Clinical AI development has traditionally followed a collaborative paradigm that depends on close interaction between clinicians and specialized AI teams. This paradigm imposes a practical challenge: clinicians must repeatedly communicate and refine their requirements with AI developers before those requirements can be translated into executable model development. This iterative process is time-consuming, and even after repeated discussion, misalignment may still exist because the two sides do not fully share each other's expertise. However, autonomous coding agents may change this paradigm, raising the possibility that clinicians could develop clinical AI models independently through natural-language interaction alone. In this study, we present such an autonomous prototype for clinician-driven clinical AI development. We evaluated the system on five clinical tasks spanning dermoscopic lesion classification, melanoma-versus-nevus triage, wrist-fracture detection (including a weakly supervised variant with only 5% bounding-box annotations), and debiased pneumothorax classification on chest radiographs. Across these settings, the system consistently developed models from clinician requests and achieved promising performance. Notably, in a debiased pneumothorax classification task on chest radiographs, where chest drains can act as a major confounder, the system successfully mitigated shortcut learning and nearly halved the model's reliance on chest drains. These findings provide proof of concept that autonomous coding agents may help shift clinical AI development toward a more clinician-driven paradigm, reducing the communication overhead and dependence on specialized AI developers. Although further validation and robustness assessment are needed, this study suggests a promising path toward making clinical AI development more accessible.

Rare diseases affect millions of individuals worldwide, yet timely diagnosis remains a major public health challenge due to scarcity of specialized clinical expertise. While large language models (LLMs) show promise to support rare disease diagnosis, current models are constrained by insufficient clinical deployability, limited clinically grounded evidence, and scarcity of training data. Here we present RaDaR (Rare Disease navigatoR), an open-source, compact reasoning LLM (32B parameters) for rare disease diagnosis. RaDaR was trained with 49,170 publicly available free-text cases and 104,666 synthetic cases with reasoning-enhanced training. RaDaR showed the strongest performance among evaluated open-source models, including the 671B DeepSeek-R1, across public benchmarks and four external validation centers. In a retrospective cohort, RaDaR prioritized the final diagnosis before documented clinical suspicion in 61.06 percent of cases, corresponding to a potential lead time of 1.87 months and 50.18 percent of the within-center interval. In a randomized physician-assistance trial, RaDaR assistance improved physicians' rare-disease diagnostic accuracy by 21.44 percentage points compared with internet search alone. Synthetic-data ablations suggested that phenotype-anchored narratives provide useful training signal for long-tail rare diseases, with a monotonic scaling trend within the tested data range. Together, RaDaR and its development and validation framework provide a deployable rare-disease reasoning model and a reproducible development framework for diagnostic AI under data scarcity.

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have significantly improved, for example, medical professional LLMs that use fine-tuning of doctor-patient Q\&A data exhibit extraordinary disease diagnostic abilities. However, we observed that despite improvements in specific domain knowledge, the performance of medical LLM in long-context understanding has significantly declined, especially compared to general language models with similar parameters. The purpose of this study is to investigate the phenomenon of reduced performance in understanding long-context in medical LLM. We designed a series of experiments to conduct open-book professional knowledge exams on all models to evaluate their ability to read long-context. By adjusting the proportion and quantity of general data and medical data in the process of fine-tuning, we can determine the best data composition to optimize the professional model and achieve a balance between long-context performance and specific domain knowledge.

Large language models (LLMs), particularly those with reasoning capabilities, have rapidly advanced in recent years, demonstrating significant potential across a wide range of applications. However, their deployment in healthcare, especially in disease reasoning tasks, is hindered by the challenge of acquiring expert-level cognitive data. In this paper, we introduce Citrus, a medical language model that bridges the gap between clinical expertise and AI reasoning by emulating the cognitive processes of medical experts. The model is trained on a large corpus of simulated expert disease reasoning data, synthesized using a novel approach that accurately captures the decision-making pathways of clinicians. This approach enables Citrus to better simulate the complex reasoning processes involved in diagnosing and treating medical conditions.To further address the lack of publicly available datasets for medical reasoning tasks, we release the last-stage training data, including a custom-built medical diagnostic dialogue dataset. This open-source contribution aims to support further research and development in the field. Evaluations using authoritative benchmarks such as MedQA, covering tasks in medical reasoning and language understanding, show that Citrus achieves superior performance compared to other models of similar size. These results highlight Citrus potential to significantly enhance medical decision support systems, providing a more accurate and efficient tool for clinical decision-making.

The emergence of general human knowledge and impressive logical reasoning capacity in rapidly progressed vision-language models (VLMs) have driven increasing interest in applying VLMs to high-level autonomous driving tasks, such as scene understanding and decision-making. However, an in-depth study on the relationship between knowledge proficiency, especially essential driving expertise, and closed-loop autonomous driving performance requires further exploration. In this paper, we investigate the effects of the depth and breadth of fundamental driving knowledge on closed-loop trajectory planning and introduce WiseAD, a specialized VLM tailored for end-to-end autonomous driving capable of driving reasoning, action justification, object recognition, risk analysis, driving suggestions, and trajectory planning across diverse scenarios. We employ joint training on driving knowledge and planning datasets, enabling the model to perform knowledge-aligned trajectory planning accordingly. Extensive experiments indicate that as the diversity of driving knowledge extends, critical accidents are notably reduced, contributing 11.9% and 12.4% improvements in the driving score and route completion on the Carla closed-loop evaluations, achieving state-of-the-art performance. Moreover, WiseAD also demonstrates remarkable performance in knowledge evaluations on both in-domain and out-of-domain datasets.

This paper explores the pitfalls in evaluating multilingual automatic speech recognition (ASR) models, with a particular focus on Indic language scripts. We investigate the text normalization routine employed by leading ASR models, including OpenAI Whisper, Meta's MMS, Seamless, and Assembly AI's Conformer, and their unintended consequences on performance metrics. Our research reveals that current text normalization practices, while aiming to standardize ASR outputs for fair comparison, by removing inconsistencies such as variations in spelling, punctuation, and special characters, are fundamentally flawed when applied to Indic scripts. Through empirical analysis using text similarity scores and in-depth linguistic examination, we demonstrate that these flaws lead to artificially improved performance metrics for Indic languages. We conclude by proposing a shift towards developing text normalization routines that leverage native linguistic expertise, ensuring more robust and accurate evaluations of multilingual ASR models.

Current large language models excel at broad, general-purpose tasks, but consistently underperform when exposed to highly specialized domains that require deep cultural, linguistic, and subject-matter expertise. In particular, traditional medical systems such as Ayurveda embody centuries of nuanced textual and clinical knowledge that mainstream LLMs fail to accurately interpret or apply. We introduce AyurParam-2.9B, a domain-specialized, bilingual language model fine-tuned from Param-1-2.9B using an extensive, expertly curated Ayurveda dataset spanning classical texts and clinical guidance. AyurParam's dataset incorporates context-aware, reasoning, and objective-style Q&A in both English and Hindi, with rigorous annotation protocols for factual precision and instructional clarity. Benchmarked on BhashaBench-Ayur, AyurParam not only surpasses all open-source instruction-tuned models in its size class (1.5--3B parameters), but also demonstrates competitive or superior performance compared to much larger models. The results from AyurParam highlight the necessity for authentic domain adaptation and high-quality supervision in delivering reliable, culturally congruent AI for specialized medical knowledge.

Leveraging pre-trained models with tailored prompts for in-context learning has proven highly effective in NLP tasks. Building on this success, recent studies have applied a similar approach to the Segment Anything Model (SAM) within a ``one-shot" framework, where only a single reference image and its label are employed. However, these methods face limitations in the medical domain, primarily due to SAM's essential requirement for visual prompts and the over-reliance on pixel similarity for generating them. This dependency may lead to (1) inaccurate prompt generation and (2) clustering of point prompts, resulting in suboptimal outcomes. To address these challenges, we introduce Med-PerSAM, a novel and straightforward one-shot framework designed for the medical domain. Med-PerSAM uses only visual prompt engineering and eliminates the need for additional training of the pretrained SAM or human intervention, owing to our novel automated prompt generation process. By integrating our lightweight warping-based prompt tuning model with SAM, we enable the extraction and iterative refinement of visual prompts, enhancing the performance of the pre-trained SAM. This advancement is particularly meaningful in the medical domain, where creating visual prompts poses notable challenges for individuals lacking medical expertise. Our model outperforms various foundational models and previous SAM-based approaches across diverse 2D medical imaging datasets.

Domain models are central to software engineering, as they enable a shared understanding, guide implementation, and support automated analyses and model-driven development. Yet, despite these benefits, practitioners often skip modeling because it is time-consuming and demands scarce expertise. We address this barrier by investigating whether open-weight large language models, adapted via instruction tuning, can generate high-quality BPMN process models directly from natural language descriptions in a cost-effective and privacy-preserving way. We introduce InstruBPM, a reproducible approach that prepares paired text-diagram data and instruction tunes an open source large language model with parameter-efficient fine-tuning and quantization for on-prem deployment. We evaluate the tuned model through complementary perspectives: (i) text/code similarity using BLEU, ROUGE-L, and METEOR, (ii) structural fidelity using Relative Graph Edit Distance, (iii) guidelines conformance using external tool checks, and (iv) a small expert review. Using a curated subset of a multi-domain BPMN dataset, we compare the tuned model with untuned open-weight baselines and strong proprietary models under consistent prompting regimes. Our compact tuned model outperforms all baselines across sequence and structural metrics while requiring substantially fewer resources; guideline analysis and expert feedback further indicate that the generated diagrams largely follow BPMN best practices and are useful starting points that reduce modeling effort. Overall, instruction tuning improves structural accuracy and robustness compared to untuned baselines and reduces reliance on heavy prompt scaffolding. We publicly share the trained models and scripts to support reproducibility and further research.

Despite remarkable advances, today's AI systems remain narrow in scope, falling short of the flexible, adaptive, and multisensory intelligence that characterizes human capabilities. This gap has fueled longstanding debates about whether AI might one day achieve human-like generality or even consciousness, and whether theories of consciousness can inspire new architectures for AI. This paper presents an early blueprint for implementing a general AI system, CTM-AI, combining the Conscious Turing Machine (CTM), a formal machine model of consciousness, with today's foundation models. CTM-AI contains an enormous number of powerful processors ranging from specialized experts (e.g., vision-language models and APIs) to unspecialized general-purpose learners poised to develop their own expertise. Crucially, for whatever problem must be dealt with, information from many processors is selected, integrated, and exchanged appropriately to solve the task. CTM-AI achieves state-of-the-art accuracy on MUStARD (72.28) and UR-FUNNY (72.13), outperforming multimodal and multi-agent frameworks. On tool-using and agentic tasks, CTM-AI achieves 10+ points of improvement on StableToolBench and WebArena-Lite. Overall, CTM-AI offers a principled, testable blueprint for general AI inspired by a model of consciousness.

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling of such medical datasets are highly challenging due to the reliance on clinical expertise and strict ethical and privacy constraints, resulting in a scarcity of large-scale unified medical datasets and hindering the development of powerful medical foundation models. In this work, we present the largest survey to date of medical image datasets, covering over 1,000 open-access datasets with a systematic catalog of their modalities, tasks, anatomies, annotations, limitations, and potential for integration. Our analysis exposes a landscape that is modest in scale, fragmented across narrowly scoped tasks, and unevenly distributed across organs and modalities, which in turn limits the utility of existing medical image datasets for developing versatile and robust medical foundation models. To turn fragmentation into scale, we propose a metadata-driven fusion paradigm (MDFP) that integrates public datasets with shared modalities or tasks, thereby transforming multiple small data silos into larger, more coherent resources. Building on MDFP, we release an interactive discovery portal that enables end-to-end, automated medical image dataset integration, and compile all surveyed datasets into a unified, structured table that clearly summarizes their key characteristics and provides reference links, offering the community an accessible and comprehensive repository. By charting the current terrain and offering a principled path to dataset consolidation, our survey provides a practical roadmap for scaling medical imaging corpora, supporting faster data discovery, more principled dataset creation, and more capable medical foundation models.

Mental health has increasingly become a global issue that reveals the limitations of traditional conversational psychotherapy, constrained by location, time, expense, and privacy concerns. In response to these challenges, we introduce SoulSpeak, a Large Language Model (LLM)-enabled chatbot designed to democratize access to psychotherapy. SoulSpeak improves upon the capabilities of standard LLM-enabled chatbots by incorporating a novel dual-memory component that combines short-term and long-term context via Retrieval Augmented Generation (RAG) to offer personalized responses while ensuring the preservation of user privacy and intimacy through a dedicated privacy module. In addition, it leverages a counseling chat dataset of therapist-client interactions and various prompting techniques to align the generated responses with psychotherapeutic methods. We introduce two fine-tuned BERT models to evaluate the system against existing LLMs and human therapists: the Conversational Psychotherapy Preference Model (CPPM) to simulate human preference among responses and another to assess response relevance to user input. CPPM is useful for training and evaluating psychotherapy-focused language models independent from SoulSpeak, helping with the constrained resources available for psychotherapy. Furthermore, the effectiveness of the dual-memory component and the robustness of the privacy module are also examined. Our findings highlight the potential and challenge of enhancing mental health care by offering an alternative that combines the expertise of traditional therapy with the advantages of LLMs, providing a promising way to address the accessibility and personalization gap in current mental health services.

Rare diseases collectively affect an estimated 3.5% to 5.9% of the population, yet more than 70% of patients are misdiagnosed and many endure years of evaluation before a diagnosis is reached, because early presentations are nonspecific and relevant expertise is scarce and unevenly distributed. Artificial intelligence could provide support, but existing systems address isolated stages of care, overwhelmingly diagnosis. They typically depend on the results of downstream investigations, and they treat the variability between models as noise to be eliminated. Here we present RareLens, a system that supports clinical decision-making across the entire rare disease trajectory by exploiting this variability. When heterogeneous large language models evaluate the same case, they generate divergent but complementary reasoning, which RareLens aligns and calibrates into a single convergent, actionable decision at each stage. Four coordinated modules perform primary-visit risk screening, diagnosis, treatment planning and prognosis. Developed and evaluated on RareBench, a real-world dataset of 157,525 cases spanning all 33 Orphanet categories and more than 7,000 conditions, RareLens outperformed every frontier model tested, including GPT-5, DeepSeek-R1, Claude-3.7-Sonnet and Gemini-2.5-Pro, at each stage. It achieved an area under the curve of 0.917 for screening and top-1 accuracies of 65.5% and 89.8% for diagnosis and treatment. In an external study spanning 1,287 cases and 23 physicians, autonomous RareLens and physicians assisted by RareLens both substantially outperformed unaided physicians. These findings indicate that aligning divergent model reasoning, rather than scaling a single model, offers a generalizable strategy for high-uncertainty clinical decision-making.

Language model users often issue queries that lack specification, where the context under which a query was issued -- such as the user's identity, the query's intent, and the criteria for a response to be useful -- is not explicit. For instance, a good response to a subjective query like "What book should I read next?" would depend on the user's preferences, and a good response to an open-ended query like "How do antibiotics work against bacteria?" would depend on the user's expertise. This makes evaluation of responses to such queries an ill-posed task, as evaluators may make arbitrary judgments about the response quality. To remedy this, we present contextualized evaluations, a protocol that synthetically constructs context surrounding an underspecified query and provides it during evaluation. We find that the presence of context can 1) alter conclusions drawn from evaluation, even flipping win rates between model pairs, 2) nudge evaluators to make fewer judgments based on surface-level criteria, like style, and 3) provide new insights about model behavior across diverse contexts. Specifically, our procedure uncovers an implicit bias towards WEIRD contexts in models' "default" responses and we find that models are not equally sensitive to following different contexts, even when they are provided in prompts.

Efficient fine-tuning of large language models for task-specific applications is imperative, yet the vast number of parameters in these models makes their training increasingly challenging. Despite numerous proposals for effective methods, a substantial memory overhead remains for gradient computations during updates. Can we fine-tune a series of task-specific small models and transfer their knowledge directly to a much larger model without additional training? In this paper, we explore weak-to-strong specialization using logit arithmetic, facilitating a direct answer to this question. Existing weak-to-strong methods often employ a static knowledge transfer ratio and a single small model for transferring complex knowledge, which leads to suboptimal performance. % To address this, To surmount these limitations, we propose a dynamic logit fusion approach that works with a series of task-specific small models, each specialized in a different task. This method adaptively allocates weights among these models at each decoding step, learning the weights through Kullback-Leibler divergence constrained optimization problems. We conduct extensive experiments across various benchmarks in both single-task and multi-task settings, achieving leading results. By transferring expertise from the 7B model to the 13B model, our method closes the performance gap by 96.4\% in single-task scenarios and by 86.3\% in multi-task scenarios compared to full fine-tuning of the 13B model. Notably, we achieve surpassing performance on unseen tasks. Moreover, we further demonstrate that our method can effortlessly integrate in-context learning for single tasks and task arithmetic for multi-task scenarios. (Our implementation is available in https://github.com/Facico/Dynamic-Logit-Fusion.)

Catastrophic forgetting remains a major challenge when adapting large language models (LLMs) to new tasks or domains. Conventional fine-tuning often overwrites existing knowledge, causing performance degradation on original tasks. We introduce Superposition in Transformers, a novel architecture that leverages autoencoders to superimpose the hidden representations of a base model and a fine-tuned model within a shared parameter space. By using B-spline-based blending coefficients and autoencoders that adaptively reconstruct hidden states based on the input data distribution, our method effectively mitigates catastrophic forgetting and enables a new paradigm of "in-model" superposition. This approach preserves original model capabilities while allowing compact domain-specific expertise to be added, and it supports dynamic switching between model states during inference.

Twenty-seven years ago, E. Freuder highlighted that "Constraint programming represents one of the closest approaches computer science has yet made to the Holy Grail of programming: the user states the problem, the computer solves it". Nowadays, CP users have great modeling tools available (like Minizinc and CPMpy), allowing them to formulate the problem and then let a solver do the rest of the job, getting closer to the stated goal. However, this still requires the CP user to know the formalism and respect it. Another significant challenge lies in the expertise required to effectively model combinatorial problems. All this limits the wider adoption of CP. In this position paper, we investigate a possible approach to leverage pre-trained Large Language Models to extract models from textual problem descriptions. More specifically, we take inspiration from the Natural Language Processing for Optimization (NL4OPT) challenge and present early results with a decomposition-based prompting approach to GPT Models.

The current generation of large language models (LLMs) is typically designed for broad, general-purpose applications, while domain-specific LLMs, especially in vertical fields like medicine, remain relatively scarce. In particular, the development of highly efficient and practical LLMs for the medical domain is challenging due to the complexity of medical knowledge and the limited availability of high-quality data. To bridge this gap, we introduce Baichuan-M1, a series of large language models specifically optimized for medical applications. Unlike traditional approaches that simply continue pretraining on existing models or apply post-training to a general base model, Baichuan-M1 is trained from scratch with a dedicated focus on enhancing medical capabilities. Our model is trained on 20 trillion tokens and incorporates a range of effective training methods that strike a balance between general capabilities and medical expertise. As a result, Baichuan-M1 not only performs strongly across general domains such as mathematics and coding but also excels in specialized medical fields. We have open-sourced Baichuan-M1-14B, a mini version of our model, which can be accessed through the following links.

TerraTorch is a fine-tuning and benchmarking toolkit for Geospatial Foundation Models built on PyTorch Lightning and tailored for satellite, weather, and climate data. It integrates domain-specific data modules, pre-defined tasks, and a modular model factory that pairs any backbone with diverse decoder heads. These components allow researchers and practitioners to fine-tune supported models in a no-code fashion by simply editing a training configuration. By consolidating best practices for model development and incorporating the automated hyperparameter optimization extension Iterate, TerraTorch reduces the expertise and time required to fine-tune or benchmark models on new Earth Observation use cases. Furthermore, TerraTorch directly integrates with GEO-Bench, allowing for systematic and reproducible benchmarking of Geospatial Foundation Models. TerraTorch is open sourced under Apache 2.0, available at https://github.com/IBM/terratorch, and can be installed via pip install terratorch.

Human cognition excels at transcending sensory input and forming latent representations that structure our understanding of the world. Although Large Language Models (LLMs) can produce chain-of-thought reasoning, they lack a principled framework to capture latent structures and model uncertainty, especially in compositional reasoning tasks. We propose Verbalized Probabilistic Graphical Modeling (vPGM), a Bayesian prompting framework that guides LLMs to simulate key principles of Probabilistic Graphical Models (PGMs) in natural language. Unlike many traditional probabilistic methods requiring substantial domain expertise or specialized training, vPGM bypasses expert-driven model design, making it well-suited for scenarios with limited assumptions or scarce data. We evaluated our model on several compositional reasoning tasks, both close-ended and open-ended. Our results indicate that the model effectively enhances confidence calibration and text generation quality.

This study investigates how to efficiently build a domain-specialized large language model (LLM) for statistics using the lightweight LLaMA-3.2-3B family as the foundation model (FM). We systematically compare three multi-stage training pipelines--starting from a base FM with no instruction-following capability, a base FM augmented with post-hoc instruction tuning, and an instruction-tuned FM with strong general reasoning abilities--across continual pretraining, supervised fine-tuning (SFT), reinforcement learning from human feedback (RLHF) preference alignment, and downstream task fine-tuning (DTFT). Results show that pipelines beginning with a base FM fail to develop meaningful statistical reasoning, even after extensive instruction tuning, SFT, or RLHF alignment. In contrast, starting from LLaMA-3.2-3B-Instruct enables effective domain specialization. A comprehensive evaluation of SFT variants reveals clear trade-offs between domain expertise and general reasoning ability. We further demonstrate that direct preference optimization provides stable and effective RLHF preference alignment. Finally, we show that DTFT must be performed with extremely low intensity to avoid catastrophic forgetting in highly optimized models. The final model, StatLLaMA, achieves strong and balanced performance on benchmarks of mathematical reasoning, common-sense reasoning, and statistical expertise, offering a practical blueprint for developing resource-efficient statistical LLMs. The code is available at https://github.com/HuangDLab/StatLLaMA.

The COVID-19 pandemic has threatened global health. Many studies have applied deep convolutional neural networks (CNN) to recognize COVID-19 based on chest 3D computed tomography (CT). Recent works show that no model generalizes well across CT datasets from different countries, and manually designing models for specific datasets requires expertise; thus, neural architecture search (NAS) that aims to search models automatically has become an attractive solution. To reduce the search cost on large 3D CT datasets, most NAS-based works use the weight-sharing (WS) strategy to make all models share weights within a supernet; however, WS inevitably incurs search instability, leading to inaccurate model estimation. In this work, we propose an efficient Evolutionary Multi-objective ARchitecture Search (EMARS) framework. We propose a new objective, namely potential, which can help exploit promising models to indirectly reduce the number of models involved in weights training, thus alleviating search instability. We demonstrate that under objectives of accuracy and potential, EMARS can balance exploitation and exploration, i.e., reducing search time and finding better models. Our searched models are small and perform better than prior works on three public COVID-19 3D CT datasets.

Ancient artifacts are an important medium for cultural preservation and restoration. However, many physical copies of artifacts are either damaged or lost, leaving a blank space in archaeological and historical studies that calls for artifact image generation techniques. Despite the significant advancements in open-domain text-to-image synthesis, existing approaches fail to capture the important domain knowledge presented in the textual description, resulting in errors in recreated images such as incorrect shapes and patterns. In this paper, we propose a novel knowledge-aware artifact image synthesis approach that brings lost historical objects accurately into their visual forms. We use a pretrained diffusion model as backbone and introduce three key techniques to enhance the text-to-image generation framework: 1) we construct prompts with explicit archaeological knowledge elicited from large language models (LLMs); 2) we incorporate additional textual guidance to correlated historical expertise in a contrastive manner; 3) we introduce further visual-semantic constraints on edge and perceptual features that enable our model to learn more intricate visual details of the artifacts. Compared to existing approaches, our proposed model produces higher-quality artifact images that align better with the implicit details and historical knowledge contained within written documents, thus achieving significant improvements across automatic metrics and in human evaluation. Our code and data are available at https://github.com/danielwusg/artifact_diffusion.